1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER

Base Information

Chemical Name:1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER
CAS No.:914672-66-5
Molecular Formula:C14H23BN2O4
Molecular Weight:294.159
Hs Code.:2934999090
Mol file:914672-66-5.mol

Synonyms:1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER;1-TERT-BUTYOXYCARBONYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-2-YL)PYRRAZOLE;1-TERT-BUTYROLYCARBONYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOLONE-2-YL)PYRAZOLE;1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole;tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Suppliers and Price of 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole
1 g
$ 920.00

SynQuest Laboratories
1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole
250 mg
$ 368.00

J&W Pharmlab
3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazole-1-carboxylicacidtert-butylester 97%
1g
$ 498.00

Crysdot
tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 95+%
250mg
$ 275.00

Crysdot
tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 95+%
1g
$ 620.00

Apolloscientific
1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole
250mg
$ 334.00

Apolloscientific
1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole
1g
$ 834.00

Ambeed
tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 98%
5g
$ 738.00

Ambeed
tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 98%
1g
$ 211.00

Ambeed
tert-Butyl3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate 98%
250mg
$ 85.00

Total 9 raw suppliers

Chemical Property of 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER

Chemical Property:

Boiling Point:387.9±34.0 °C(Predicted)
PKA:-1.34±0.12(Predicted)
PSA：62.58000
Density:1.09±0.1 g/cm3(Predicted)
LogP:1.96550
Storage Temp.:Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

1-tert-Butoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)pyrazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER

There total 2 articles about 1-TERT-BUTYLOXYCARBONYLPYRAZOLE-3-BORONIC ACID PINACOL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121669-70-3
4-iodo-1H-pyrazole-1-carboxylic acid tert-butyl ester

: 61676-62-8
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 914672-66-5
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Guidance literature:: With isopropylmagnesium chloride; In tetrahydrofuran; at 0 - 20 ℃; for 3.5h; Inert atmosphere;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 914672-66-5
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / tetrahydrofuran / 3 h / 15 °C / Inert atmosphere

2: isopropylmagnesium chloride / tetrahydrofuran / 3.5 h / 0 - 20 °C / Inert atmosphere

With dmap; isopropylmagnesium chloride; In tetrahydrofuran;

Reference yield: 59.0%

: 914672-66-5
tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

: 7-bromo-2-(3-(3,4-difluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine

: 2-(3-(3 ,4-difluorophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)-7-(1H-pyrazol-4-yl)-1,5-naphthyridine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In 1,4-dioxane; water; at 100 ℃; for 16h; Inert atmosphere;