5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE

Base Information

Chemical Name:5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE
CAS No.:872254-89-2
Molecular Formula:C13H11F3N2
Molecular Weight:252.239
Hs Code.:
Mol file:872254-89-2.mol

Synonyms:5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE;5-methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine

Suppliers and Price of 5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine 97%
1g
$ 490.00

A1 Biochem Labs
5-Amino-3-methyl-2-(4-(trifluoromethyl)phenyl)pyridine 95%
2.5 g
$ 1200.00

Total 7 raw suppliers

Chemical Property of 5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE

Chemical Property:

Boiling Point:327.3±37.0 °C(Predicted)
PKA:5.06±0.25(Predicted)
PSA：38.91000
Density:1.261±0.06 g/cm3(Predicted)
LogP:4.23920

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE

There total 4 articles about 5-AMINO-3-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 872254-88-1
3-methyl-5-nitro-2-(4-trifluoromethyl-phenyl)-pyridine

: 872254-89-2
5-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 3h; under 2585.81 Torr;

Reference yield:

: 22280-56-4
2-chloro-3-methyl-5-nitropyridine

: 872254-89-2
5-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium fluoride / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / ethanol / 4 h / 775.74 Torr

With potassium fluoride; hydrogen; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; In ethanol; toluene; 1: Suzuki Coupling;

Reference yield:

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 872254-89-2
5-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium fluoride / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / ethanol / 4 h / 775.74 Torr

With potassium fluoride; hydrogen; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; In ethanol; toluene; 1: Suzuki Coupling;