(2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid

Base Information

Chemical Name:(2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid
CAS No.:1228568-48-6
Molecular Formula:C9H8F3NO2
Molecular Weight:219.16
Hs Code.:
DSSTox Substance ID:DTXSID40363565
Nikkaji Number:J1.917.964H
Mol file:1228568-48-6.mol

Synonyms:1228568-48-6;(2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid;(S)-2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID;(S)-alpha-Amino-3-(trifluoromethyl)benzeneacetic acid;(S)-AMINO-(3-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID;DTXSID40363565;2-(3-Trifluoromethylphenyl)glycine;3-(Trifluoromethyl)-L-phenylglycine;MFCD00236328;AKOS015926578;AT34090;CS-0334838;(S)-2-AMINO-2-(3-(TRIFLUOROMETHYL)PHENYL)ACETICACID;(S)-2-Amino-2-(3-(trifluoromethyl)phenyl)acetic acid (H-L-Phg(3-CF3)-OH)

Suppliers and Price of (2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-Amino-2-(3-(trifluoromethyl)phenyl)aceticacid 95+%
1g
$ 405.00

Chemenu
(S)-2-Amino-2-(3-(trifluoromethyl)phenyl)aceticacid 95%
1g
$ 492.00

Activate Scientific
(S)-alpha-Amino-3-(trifluoromethyl)benzeneacetic acid 95+% ee
250 mg
$ 236.00

Activate Scientific
(S)-alpha-Amino-3-(trifluoromethyl)benzeneacetic acid 95+% ee
1 g
$ 491.00

Activate Scientific
(S)-alpha-Amino-3-(trifluoromethyl)benzeneacetic acid 95+% ee
5 g
$ 1368.00

Acrotein
(S)-a-Amino-3-(trifluoromethyl)benzeneaceticacid 97%
0.25g
$ 151.43

Acrotein
(S)-a-Amino-3-(trifluoromethyl)benzeneaceticacid 97%
1g
$ 346.50

Acrotein
(S)-a-Amino-3-(trifluoromethyl)benzeneaceticacid 97%
0.5g
$ 229.17

ACHEMBLOCK
(S)-a-Amino-3-(trifluoromethyl)benzeneaceticacid 95%
250MG
$ 185.00

Total 4 raw suppliers

Chemical Property of (2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid

Chemical Property:

PSA：63.32000
LogP:2.49010
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:219.05071298
Heavy Atom Count:15
Complexity:242

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-Amino-2-(3-(trifluoromethyl)phenyl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)C(C(=O)O)N
Isomeric SMILES:C1=CC(=CC(=C1)C(F)(F)F)[C@@H](C(=O)O)N

Technology Process of (2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid

There total 2 articles about (2S)-2-amino-2-[3-(trifluoromethyl)phenyl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1404627-68-4
C₁₁H₁₀F₃NO₃

: C₁₁H₁₀F₃NO₃

: 1228568-48-6,1228548-29-5
(S)-2-amino-2-(3-(trifluoromethyl)phenyl)acetic acid

Guidance literature:: With lipase AS 'Amano'; at 35 ℃; for 24h; pH=6.5; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.tetasy.2012.08.017

Reference yield:

: 242475-26-9,1228548-29-5
2-amino-2-(3-(trifluoromethyl)phenyl)acetic acid

: C₁₁H₁₀F₃NO₃

: 1228568-48-6,1228548-29-5
(S)-2-amino-2-(3-(trifluoromethyl)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / water; N,N-dimethyl-formamide / 20 °C

2: lipase AS 'Amano' / 24 h / 35 °C / pH 6.5 / Enzymatic reaction

With lipase AS 'Amano'; triethylamine; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2012.08.017