5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

Base Information

Chemical Name:5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one
CAS No.:152368-17-7
Molecular Formula:C10H13NO4
Molecular Weight:211.218
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50391410
Wikidata:Q82188861
Mol file:152368-17-7.mol

Synonyms:152368-17-7;5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one;5-hydroxy-2-(morpholin-4-ylmethyl)pyran-4-one;5-HYDROXY-2-(4-MORPHOLINYLMETHYL)-4H-PYRAN-4-ONE;5-hydroxy-2-(morpholin-4-ylmethyl)-4H-pyran-4-one;5-hydroxy-2-[(morpholin-4-yl)methyl]-4H-pyran-4-one;5-hydroxy-2-(4-morpholinylmethyl)-4H-pyran-4-one(SALTDATA: FREE);SCHEMBL4160504;DTXSID50391410;IYSJGXVZXRIYPD-UHFFFAOYSA-N;CGA36817;BBL036793;MFCD04122633;STK934814;AKOS005208378;VS-13696;EN300-237612

Suppliers and Price of 5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Hydroxy-2-(morpholin-4-ylmethyl)-4H-pyran-4-one
100mg
$ 60.00

ChemBridge Corporation
5-hydroxy-2-(4-morpholinylmethyl)-4H-pyran-4-one 95%
10 g
$ 224.00

American Custom Chemicals Corporation
5-HYDROXY-2-(4-MORPHOLINYLMETHYL)-4H-PYRAN-4-ONE 95.00%
10G
$ 2279.97

American Custom Chemicals Corporation
5-HYDROXY-2-(4-MORPHOLINYLMETHYL)-4H-PYRAN-4-ONE 95.00%
1G
$ 818.61

Total 5 raw suppliers

Chemical Property of 5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

Chemical Property:

Boiling Point:390.5±42.0 °C(Predicted)
PKA:8.17±0.10(Predicted)
PSA：62.91000
Density:1.356±0.06 g/cm3(Predicted)
LogP:0.11550
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:211.08445790
Heavy Atom Count:15
Complexity:315

Purity/Quality:

97% ^*data from raw suppliers

5-Hydroxy-2-(morpholin-4-ylmethyl)-4H-pyran-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1CC2=CC(=O)C(=CO2)O

Technology Process of 5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

There total 2 articles about 5-Hydroxy-2-(morpholinomethyl)-4H-pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 110-91-8,99108-56-2
morpholine

: 40838-28-6
6-bromomethyl-3-hydroxy-4H-pyran-4-one

: 152368-17-7
5-hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

Guidance literature:: In acetonitrile; at 80 ℃; for 3h;

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 152368-17-7
5-hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 11.5 h / 0 - 70 °C

2: acetonitrile / 3 h / 80 °C

With sulfuric acid; In acetonitrile;

Reference yield: 99.0%

: 152368-17-7
5-hydroxy-2-(morpholinomethyl)-4H-pyran-4-one

: 102-96-5
(2-nitroethenyl)benzene

: (R)-3-hydroxy-6-(morpholinomethyl)-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one

Guidance literature:: With 3,4-bis(((1R,2R)-2-(piperidin-1-yl)cyclohexyl)amino)cyclobut-3-ene-1,2-dione; In ethanol; at 20 ℃; for 6h; enantioselective reaction; Green chemistry;
DOI:10.1021/acs.joc.9b00252