6|A-Hydroxy Norethindrone Acetate

Base Information

• Chemical Name: 6|A-Hydroxy Norethindrone Acetate
• CAS No.: 6856-27-5
• Molecular Formula: C₂₂H₂₈O₄
• Molecular Weight: 356.462
• European Community (EC) Number: 641-818-3
• UNII: WJX543VUS5
• DSSTox Substance ID: DTXSID50462114
• Nikkaji Number: J1.691.122D
• Wikidata: Q82286608
• Mol file: 6856-27-5.mol

Synonyms:6856-27-5;6|A-Hydroxy Norethindrone Acetate;6beta-Hydroxy Norethindrone Acetate;6ss-Hydroxynorethindrone acetate;[(6R,8R,9S,10R,13S,14S,17R)-17-ethynyl-6-hydroxy-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate;6?-Hydroxy Norethindrone Acetate;Norethisterone Acetate Imp. F (EP);6beta-Hydroxy-3-oxo-19-nor-17alpha-pregn-4-en-20-yn-17-yl Acetate;6beta-Hydroxynorethisterone Acetate;Norethisterone Acetate Impurity F;WJX543VUS5;SCHEMBL5722719;DTXSID50462114;19-NOrpregn-4-en-20-yn-3-one, 17-(acetyloxy)-6-hydroxy-, (6|A,17|A)-;6beta-Hydroxy-3-oxo-19-nor-17alpha-pregn-4-en-20-yn-17-yl Acetate (6beta-Hydroxynorethisterone Acetate);AKOS032958248;6.BETA.-HYDROXYNORETHINDRONE ACETATE;NORETHISTERONE ACETATE IMPURITY F [EP IMPURITY];19-NORPREGN-4-EN-20-YN-3-ONE, 17-(ACETYLOXY)-6-HYDROXY-, (6.BETA.,17.ALPHA.)-

Chemical Property of 6|A-Hydroxy Norethindrone Acetate

Chemical Property:

• PSA: 63.60000
• LogP: 3.03410
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 356.19875937
• Heavy Atom Count: 26
• Complexity: 728

Purity/Quality:

95% ^*data from raw suppliers

6β-HydroxyNorethindroneAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1(CCC2C1(CCC3C2CC(C4=CC(=O)CCC34)O)C)C#C
• Isomeric SMILES: CC(=O)O[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@H](C4=CC(=O)CC[C@H]34)O)C)C#C
• Uses: 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity. An oxidative product of the drug Norethindrone

Technology Process of 6|A-Hydroxy Norethindrone Acetate

There total 1 articles about 6|A-Hydroxy Norethindrone Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 17α-Ethinyl-17β-acetoxy-6β-hydroxy-oestr-4-en-3-on (6856-27-5,6856-28-6)

Guidance literature:

3-Cyclopentyloxy-17α-ethinyl-17β-acetoxy-oestr-3,5-dien, A., THF, Sonnenlicht;

DOI:10.1021/jo01283a071