9a-aza-9a-homo Erythromycin A

Base Information

• Chemical Name: 9a-aza-9a-homo Erythromycin A
• CAS No.: 76820-32-1
• Molecular Formula: C₃₇H₆₈N₂O₁₃
• Molecular Weight: 748.953
• Mol file: 76820-32-1.mol

Synonyms:9a-aza-9a-homo Erythromycin A;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexaMethyl-11-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-1-o;9a-aza-9a-hoMo ErythroMycin A (~90%)

Chemical Property of 9a-aza-9a-homo Erythromycin A

Chemical Property:

• PSA: 205.94000
• LogP: 1.41390
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly) Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

9a-aza-9a-homoErythromycinA ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Novel intermediate of Azithromycin that acts as antibiotic

Technology Process of 9a-aza-9a-homo Erythromycin A

There total 1 articles about 9a-aza-9a-homo Erythromycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

erythromycin A oxime (13127-18-9,92470-22-9,111321-02-9,134931-01-4) → erythromycin A lactam (76820-32-1,92470-23-0)

Guidance literature:

With pyridine; p-toluenesulfonyl chloride; In diethyl ether; at 0 - 5 ℃; for 2h;

upstream raw materials:

erythromycin A oxime

Refernces