4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile

Base Information

Chemical Name:4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile
CAS No.:82183-24-2
Molecular Formula:C₇H₇ClN₄
Molecular Weight:182.612
Hs Code.:2933599090
DSSTox Substance ID:DTXSID40513402
Wikidata:Q82373202
Mol file:82183-24-2.mol

Synonyms:4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile;82183-24-2;DTXSID40513402;SB56529

Suppliers and Price of 4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile 95+%
1g
$ 880.00

Chemenu
4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile 95%
1g
$ 830.00

Alichem
4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile
1g
$ 721.14

Total 6 raw suppliers

Chemical Property of 4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile

Chemical Property:

Melting Point:149-150 °C(Solv: benzene (71-43-2))
Boiling Point:342.4±45.0 °C(Predicted)
PKA:0.67±0.10(Predicted)
PSA：52.81000
Density:1.34±0.1 g/cm3(Predicted)
LogP:1.06768
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:182.0359239
Heavy Atom Count:12
Complexity:197

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=NC=C(C(=N1)Cl)C#N

Technology Process of 4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile

There total 4 articles about 4-Chloro-2-(dimethylamino)pyrimidine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89852-94-8
2-dimethylamino-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile

: 82183-24-2
4-chloro-2-dimethylamino-pyrimidine-5-carbonitrile

Guidance literature:: With trichlorophosphate;
DOI:10.1002/hlca.19590420318

Reference yield:

: 89487-99-0
5-cyano-2-methylsulfanyl-4(3H)-pyrimidinone

: 82183-24-2
4-chloro-2-dimethylamino-pyrimidine-5-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

2: POCl₃

With trichlorophosphate;
DOI:10.1002/hlca.19590420318

Reference yield:

: 90322-13-7
C₈H₁₁N₃O₂S

: 82183-24-2
4-chloro-2-dimethylamino-pyrimidine-5-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH solution

3: POCl₃

With sodium hydroxide; trichlorophosphate;
DOI:10.1002/hlca.19590420318