2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid

Base Information

Chemical Name:2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid
CAS No.:445029-32-3
Molecular Formula:C14H18O2
Molecular Weight:218.296
Hs Code.:
DSSTox Substance ID:DTXSID601334214
Mol file:445029-32-3.mol

Synonyms:445029-32-3;2-(4-(tert-butyl)phenyl)cyclopropanecarboxylic acid;2-(4-tert-Butyl-phenyl)-cyclopropanecarboxylic acid;2-(4-tert-butylphenyl)cyclopropane-1-carboxylic acid;2-(4-tert-butylphenyl)cyclopropanecarboxylic acid;2-(4-(tert-butyl)phenyl)cyclopropane-1-carboxylic acid;SCHEMBL301271;ANPQFLQUUUWDQU-UHFFFAOYSA-N;DTXSID601334214;MFCD02056423;AKOS000311113;VS-03663;CS-0217758;EN300-83734;2-(4-(tert-butyl)phenyl)cyclopropanecarboxylicacid;2-[4-(t-butyl)phenyl]cyclopropanecarboxylic acid;2-[4-(TERT-BUTYL)PHENYL]-1-CYCLOPROPANECARBOXYLIC ACID

Suppliers and Price of 2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-tert-butylphenyl)cyclopropanecarboxylicAcid
100mg
$ 220.00

TRC
2-(4-tert-butylphenyl)cyclopropanecarboxylicAcid
50mg
$ 155.00

Crysdot
2-(4-(tert-Butyl)phenyl)cyclopropanecarboxylicacid 95+%
1g
$ 429.00

Chemenu
2-(4-(tert-butyl)phenyl)cyclopropane-1-carboxylicacid 95%
1g
$ 405.00

American Custom Chemicals Corporation
2-(4-TERT-BUTYLPHENYL)CYCLOPROPANE-1-CARBOXYLIC ACID 95.00%
5MG
$ 495.79

Alichem
2-(4-(tert-Butyl)phenyl)cyclopropanecarboxylicacid
1g
$ 353.50

Total 8 raw suppliers

Chemical Property of 2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid

Chemical Property:

PSA：37.30000
LogP:3.17220
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.130679813
Heavy Atom Count:16
Complexity:269

Purity/Quality:

97% ^*data from raw suppliers

2-(4-tert-butylphenyl)cyclopropanecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C2CC2C(=O)O

Technology Process of 2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid

There total 5 articles about 2-(4-(Tert-butyl)phenyl)cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 105393-24-6
2-[4-(tert-butyl)phenyl]cyclopropylmethanol

: 445029-32-3,105393-30-4
2-[4-(tert-butyl)phenyl]cyclopropanecarboxylic acid

Guidance literature:: With dipyridinium dichromate; In N,N-dimethyl-formamide; for 24h; Molecular sieve;

Reference yield:

: 105393-23-5
2-(4-tert-butylphenyl)cyclopropane-1-carboxylic acid ethyl ester

: 445029-32-3,105393-30-4
2-[4-(tert-butyl)phenyl]cyclopropanecarboxylic acid

Guidance literature:: With potassium hydroxide; sodium chloride; In methanol; water;

Reference yield:

: 158010-17-4
ethyl (E)-3-[4-(tert-butylphenyl)]-2-propenoate

: 445029-32-3,105393-30-4
2-[4-(tert-butyl)phenyl]cyclopropanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: diisobutylaluminium hydride / dichloromethane; toluene / 3 h / -78 °C

2.1: diethylzinc / dichloromethane; hexane / 0.08 h / 0 °C

2.2: 4 h

3.1: dipyridinium dichromate / N,N-dimethyl-formamide / 12 h / 20 °C / Molecular sieve

With dipyridinium dichromate; diethylzinc; diisobutylaluminium hydride; In hexane; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1007/s12272-013-0228-x