N-acetylsphingosine

Base Information

Chemical Name:N-acetylsphingosine
CAS No.:3102-57-6
Molecular Formula:C20H39 N O3
Molecular Weight:341.535
Hs Code.:29241990
UNII:8YTC7R47CW
DSSTox Substance ID:DTXSID201016802
Nikkaji Number:J853.911A,J640.711K
Wikidata:Q27120742
NCI Thesaurus Code:C63674
Metabolomics Workbench ID:30574
ChEMBL ID:CHEMBL105867
Mol file:3102-57-6.mol

Synonyms:C2-ceramide;N-acetylsphingosine

Suppliers and Price of N-acetylsphingosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
C2 Ceramide
5mg
$ 319.00

TRC
C2Ceramide
10mg
$ 50.00

TRC
C2Ceramide
500mg
$ 90.00

SynQuest Laboratories
C2 Ceramide
10 mg
$ 317.00

SynQuest Laboratories
C2 Ceramide
5 mg
$ 184.00

Sigma-Aldrich
N-Acetyl-D-sphingosine ≥98.0% (TLC)
50mg
$ 172.00

Sigma-Aldrich
N-Acetyl-D-sphingosine
5mg
$ 114.00

Sigma-Aldrich
N-Acetyl-D-sphingosine ≥97% (TLC), powder
5mg
$ 82.50

Sigma-Aldrich
N-Acetyl-D-sphingosine ≥97% (TLC), powder
1mg
$ 31.00

Sigma-Aldrich
N-Acetyl-D-sphingosine ≥98.0% (TLC)
250mg
$ 615.00

Total 16 raw suppliers

Chemical Property of N-acetylsphingosine

Chemical Property:

Vapor Pressure:1.48E-13mmHg at 25°C
Melting Point:93-96 °C
Refractive Index:1.5614 (estimate)
Boiling Point:532.4°Cat760mmHg
PKA:13.50±0.20(Predicted)
Flash Point:275.8°C
PSA：69.56000
Density:0.964g/cm³
LogP:4.49250
Storage Temp.:−20°C
Solubility.:DMSO: soluble
XLogP3:5.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:16
Exact Mass:341.29299411
Heavy Atom Count:24
Complexity:318

Purity/Quality:

98%,99%, ^*data from raw suppliers

C2 Ceramide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCCCCCCCCCCCC=CC(C(CO)NC(=O)C)O
Isomeric SMILES:CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)C)O
Description C2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides. These processes include differentiation of HL-60 cells, induction of apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. C2 ceramide also enhances the expression of COX-2 in human dermal fibroblasts and stimulates the growth of bovine aortic smooth muscle cells. The ability of C2 ceramide to destabilize membranes may be responsible for its inhibition of platelet aggregation.
Uses Inhibits cell proliferation and induces monocytic differentiation of HL-60 cells. Activates protein phosphatases A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2

Technology Process of N-acetylsphingosine

There total 38 articles about N-acetylsphingosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%