trifluoroacetyldaunomycin

Base Information

Chemical Name:trifluoroacetyldaunomycin
CAS No.:26388-52-3
Molecular Formula:C29H28F3NO11
Molecular Weight:623.537
Hs Code.:
Mol file:26388-52-3.mol

Synonyms:trifluoroacetyldaunomycin;N-(Trifluoroacetyl)daunorubicin;(8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)aMino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione

Suppliers and Price of trifluoroacetyldaunomycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(Trifluoroacetyl)daunorubicin
1mg
$ 90.00

Total 5 raw suppliers

Chemical Property of trifluoroacetyldaunomycin

Chemical Property:

Vapor Pressure:3.15E-28mmHg at 25°C
Melting Point:>173°C (dec.)
Boiling Point:817°C at 760 mmHg
PKA:7.39±0.60(Predicted)
Flash Point:447.9°C
PSA：192.41000
Density:1.61g/cm³
LogP:2.58900
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

N-(Trifluoroacetyl)daunorubicin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Protected Daunorubicin.

Technology Process of trifluoroacetyldaunomycin

There total 7 articles about trifluoroacetyldaunomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 26295-55-6
14-iodo-N-(trifluoroacetyl)daunorubicin

: 26388-52-3,52471-41-7,64686-33-5
3'-N-trifluoroacetyldaunorubicin

Guidance literature:: With potassium carbonate; thiophenol; In ethanol; for 0.166667h; Ambient temperature;
DOI:10.1021/jo00325a038

Reference yield: 99.0%

: 23541-50-6
daunomycin hydrochloride

: 407-25-0
trifluoroacetic anhydride

: 26388-52-3,52471-41-7,64686-33-5
3'-N-trifluoroacetyldaunorubicin

Guidance literature:: With pyridine; In diethyl ether; at -20 ℃; for 0.166667h;
DOI:10.1021/jm00157a026

Reference yield: 95.0%

: daunorubicin hydrochloride

: 407-25-0
trifluoroacetic anhydride

: 26388-52-3,52471-41-7,64686-33-5
3'-N-trifluoroacetyldaunorubicin

Guidance literature:: daunorubicin hydrochloride; trifluoroacetic anhydride; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

With sodium hydrogencarbonate; In methanol; dichloromethane; water; at 20 ℃; pH=7 - 8; Temperature;