Zoledronic Acid Trihydrate

Base Information

Chemical Name:Zoledronic Acid Trihydrate
CAS No.:904894-54-8
Molecular Formula:C₅H₁₀N₂O₇P₂*H₂O
Molecular Weight:290.106
Hs Code.:
UNII:Y1X5LD5UCA
Wikidata:Q27294157

Synonyms:Zoledronic Acid Trihydrate;1-Hydroxy-2-(1H-iMidazol-1-yl)ethylidene]-bisphosphonic Acid Trihydrate;2-(IMidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic Acid Trihydrate

Suppliers and Price of Zoledronic Acid Trihydrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Zoledronic Acid Trihydrate

Chemical Property:

Melting Point:232-235°C (dec.)
PSA：200.42000
LogP:-1.30830
Storage Temp.:Refrigerator
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:4
Exact Mass:326.02801871
Heavy Atom Count:19
Complexity:327

Purity/Quality:: 99.99%HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O.O.O.O
Uses Bisphosphonate antiresorptive agent.

Technology Process of Zoledronic Acid Trihydrate

There total 5 articles about Zoledronic Acid Trihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 22884-10-2
imidazol-1-ylacetic acid

: 904894-54-8
zoledronic acid dihydrate

Guidance literature:: imidazol-1-ylacetic acid; With 1-butyl-3-methylimidazolium Tetrafluoroborate; phosphorous acid; phosphorus trichloride; In sulfolane; at 75 ℃; for 0.5h; Ionic liquid;

With water; at 105 ℃; for 1h; pH=1.8; Reagent/catalyst;
DOI:10.1080/00397911.2017.1410894