3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-

Base Information

• Chemical Name: 3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-
• CAS No.: 915364-18-0
• Molecular Formula: C16H9Cl2FN4
• Molecular Weight: 347.1738632
• Mol file: 915364-18-0.mol

Synonyms:3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-;6-amino-8-chloro-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile

Chemical Property of 3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-

Chemical Property:

• Vapor Pressure: 1.31E-11mmHg at 25°C
• Boiling Point: 537.1°C at 760 mmHg
• PKA: 1.56±0.50(Predicted)
• Flash Point: 278.7°C
• PSA: 74.73000
• Density: 1.54g/cm³
• LogP: 5.53238

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-Quinolinecarbonitrile,6-amino-8-chloro-4-[(3-chloro-4-fluorophenyl)amino]- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-

There total 2 articles about 3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H7Cl2FN4O2 → 6-amino-8-chloro-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (915364-18-0)

Guidance literature:

With ethanol; tin(ll) chloride; at 110 ℃; for 0.0833333h; microwave irradiation;

DOI:10.1021/jm070436q

Reference yield:

→ 6-amino-8-chloro-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (915364-18-0)

Guidance literature:

Reference yield: 78.0%

1-methylimidazole-5-carbaldehyde (39021-62-0) + 6-amino-8-chloro-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile (915364-18-0) → 8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-{[(1-methyl-1H-imidazol-5-yl)methyl]amino}quinoline-3-carbonitrile

Guidance literature:

1-methylimidazole-5-carbaldehyde; 6-amino-8-chloro-4-((3-chloro-4-fluorophenyl)amino)quinoline-3-carbonitrile; In tetrahydrofuran; methanol;

With sodium cyanoborohydride; In tetrahydrofuran; methanol; ethanol; Further stages.;

DOI:10.1021/jm070436q

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 915364-18-0 3-Quinolinecarbonitrile, 6-aMino-8-chloro-4-[(3-chloro-4-fluorophenyl)aMino]-

Send

Send

Metric Ton KG G Pound L ML

Send

Send