N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester

Base Information

• Chemical Name: N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester
• CAS No.: 915979-44-1
• Molecular Formula: C23H22F3NO2
• Molecular Weight: 401.428

Synonyms:N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester;3-(3-(trifluoromethyl)phenyl)propyl

Chemical Property of N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester

Chemical Property:

• PSA: 38.33000
• LogP: 6.66950

Purity/Quality:

99% ^*data from raw suppliers

N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester ^*data from reagent suppliers

Safty Information:

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Technology Process of N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester

There total 1 articles about N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.17%

3-[3-(trifluoromethyl)phenyl]propan-1-ol (78573-45-2) + C13H12ClNO → (R)-(1-naphthalen-1-ylethyl)carbamic acid 3-(3-trifluoromethylphenyl)propyl ester (915979-44-1)

Guidance literature:

With pyridine; In dichloromethane; at -2 - 22 ℃; for 16.5h; Temperature; Inert atmosphere;

Reference yield:

(R)-(1-naphthalen-1-ylethyl)carbamic acid 3-(3-trifluoromethylphenyl)propyl ester (915979-44-1) + methylsulfonyl-3-(3-trifluoromethylphenyl)propyl ester (21172-43-0) → C33H31F6NO2 (1204313-94-9)

Guidance literature:

With sodium hydroxide; In dimethyl sulfoxide; at 25 - 30 ℃; for 20h;

upstream raw materials:

3-[3-(trifluoromethyl)phenyl]propan-1-ol

Downstream raw materials:

C₃₃H₃₁F₆NO₂

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