Chemical Property of CID 13206344
Chemical Property:
- Vapor Pressure:4.94E-31mmHg at 25°C
- Melting Point:145-150°
- Refractive Index:1.5300 (estimate)
- Boiling Point:818.4 °C at 760 mmHg
- Flash Point:448.8 °C
- PSA:411.51000
- Density:0.9083 (rough estimate)
- LogP:-3.88330
- Storage Temp.:Refrigerator
- Solubility.:Soluble in water, freely soluble in anhydrous ethanol and in methanol, very slightly soluble in acetone and in methylene chloride.
- Water Solubility.:>20g/L(21 oC)
- Hydrogen Bond Donor Count:14
- Hydrogen Bond Acceptor Count:26
- Rotatable Bond Count:15
- Exact Mass:1091.57236732
- Heavy Atom Count:75
- Complexity:1580
- Purity/Quality:
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99% *data from raw suppliers
ErythromycinLactobionate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
- Recent ClinicalTrials:ANTERO-4: VIPUN Gastric Monitoring System in an Erythromycin Model
- Recent EU Clinical Trials:The Impact of Target Temperature Management on Drug Metabolism
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Description
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
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Uses
Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs. Macrolide antibacterial.
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Therapeutic Function
Antibacterial