3-(3-Fluorophenyl)azetidine

Base Information

• Chemical Name: 3-(3-Fluorophenyl)azetidine
• CAS No.: 1203798-80-4
• Molecular Formula: C₉H₁₀FN
• Molecular Weight: 151.184
• Mol file: 1203798-80-4.mol

Synonyms:3-(3-Fluorophenyl)azetidine

Chemical Property of 3-(3-Fluorophenyl)azetidine

Chemical Property:

• PSA: 12.03000
• LogP: 1.84130

Purity/Quality:

97% ^*data from raw suppliers

3-(3-Fluorophenyl)azetidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-(3-Fluorophenyl)azetidine is a 3-phenylazetidine derivative used in the preparation of pyridinyl amides for treatment of CNS and metabolic disorders.

Technology Process of 3-(3-Fluorophenyl)azetidine

There total 1 articles about 3-(3-Fluorophenyl)azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 3-(3-fluorophenyl)azetidine-1-carboxylate (1412977-14-0) → 3-(3-fluorophenyl)azetidine (1203798-80-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2017.10.053

upstream raw materials:

tert-butyl 3-(3-fluorophenyl)azetidine-1-carboxylate

Refernces