2,4'-Dichloro-3'-methylbenzophenone

Base Information

• Chemical Name: 2,4'-Dichloro-3'-methylbenzophenone
• CAS No.: 74617-45-1
• Molecular Formula: C₁₄H₁₀Cl₂O
• Molecular Weight: 265.139
• Hs Code.: 2914700090
• DSSTox Substance ID: DTXSID10504408
• Wikidata: Q82358888
• Mol file: 74617-45-1.mol

Synonyms:2,4'-DICHLORO-3'-METHYLBENZOPHENONE;74617-45-1;(4-chloro-3-methylphenyl)-(2-chlorophenyl)methanone;MFCD09801508;DTXSID10504408;AKOS016018534;(4-Chloro-3-methylphenyl)(2-chlorophenyl)methanone;(4-Chloro-3-methyl-phenyl)-(2-chloro-phenyl)-methanone

Chemical Property of 2,4'-Dichloro-3'-methylbenzophenone

Chemical Property:

• Vapor Pressure: 2.02E-06mmHg at 25°C
• Boiling Point: 394.2°C at 760 mmHg
• Flash Point: 166.6°C
• PSA: 17.07000
• Density: 1.276g/cm³
• LogP: 4.53280
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 264.0108703
• Heavy Atom Count: 17
• Complexity: 279

Purity/Quality:

97% ^*data from raw suppliers

2,4'-Dichloro-3'-methylbenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)C(=O)C2=CC=CC=C2Cl)Cl

Technology Process of 2,4'-Dichloro-3'-methylbenzophenone

There total 1 articles about 2,4'-Dichloro-3'-methylbenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylchlorobenzene (95-49-8) + o-chlorobenzoyl chloride (609-65-4) → 2,4'-dichloro-3'-methyl-benzophenone (74617-45-1)

Guidance literature:

With carbon disulfide; aluminium trichloride;

Reference yield:

2,4'-dichloro-3'-methyl-benzophenone (74617-45-1) → 3-(4-Chloro-3-methyl-phenyl)-benzo[d]isothiazole (74617-07-5)

Guidance literature:

With ammonia; In various solvent(s); at 160 ℃; for 6h; Yield given;

Reference yield:

2,4'-dichloro-3'-methyl-benzophenone (74617-45-1) → o-(4-Chloro-3-methyl)benzoyl benzoic acid (141123-11-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 200 °C / im Rohr

2: aqueous KOH-solution

With pyridine; potassium hydroxide;

upstream raw materials:

2-methylchlorobenzene

o-chlorobenzoyl chloride

Downstream raw materials:

3-(4-Chloro-3-methyl-phenyl)-benzo[d]isothiazole

(4-chloro-3-methylphenyl)(phenyl)methanone

o-(4-Chloro-3-methyl)benzoyl benzoic acid