(4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID

Base Information

Chemical Name:(4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID
CAS No.:207497-61-8
Molecular Formula:C₁₆H₁₇NO₄
Molecular Weight:287.315
Hs Code.:2922499990
Mol file:207497-61-8.mol

Synonyms:(4S)-4-(2-Naphthylmethyl)-L-glutamic acid; L-Glutamic acid, 4-(2-naphthalenylmethyl)-, (4S)-

Suppliers and Price of (4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2S,4S)-2-Amino-4-(naphthalen-2-ylmethyl)pentanedioicacid 95+%
1g
$ 866.00

Chemenu
(2S,4S)-2-Amino-4-(naphthalen-2-ylmethyl)pentanedioicacid 95%
1g
$ 817.00

American Custom Chemicals Corporation
(2S,4S)-2-AMINO-4-NAPHTHALEN-2-YLMETHYL-PENTANEDIOIC ACID 95.00%
500MG
$ 1061.16

Total 14 raw suppliers

Chemical Property of (4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID

Chemical Property:

Vapor Pressure:2.85E-12mmHg at 25°C
Boiling Point:534.9°C at 760 mmHg
Flash Point:277.3°C
PSA：100.62000
Density:1.329g/cm³
LogP:2.58540

Purity/Quality:

97% ^*data from raw suppliers

(2S,4S)-2-Amino-4-(naphthalen-2-ylmethyl)pentanedioicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID

There total 10 articles about (4S)-4-(NAPHTHALEN-2-YLMETHYL)-L-GLUTAMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 862583-27-5
1-tert-butyl 2-methyl (2S,4R)-4-(2-naphthylmethyl)-5-oxopyrrolidine-1,2-dicarboxylate

: 1356090-80-6,207497-61-8
(2S,4R)-2-amino-4-(2-naphthylmethyl)pentanedioic acid

Guidance literature:: With hydrogenchloride; for 4h; Heating;
DOI:10.1002/ejoc.200400916

Reference yield:

: 66-99-9
β-naphthaldehyde

: 207497-61-8
(2S,4S)-2-Amino-4-naphthalen-2-ylmethyl-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) lithium hexamethyldisilazide, 2.) BF₃*Et₂O / 1.) THF, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h

2: MsCl, Et₃N / CH₂Cl₂ / 48 h / Ambient temperature

3: H₂ / PtO₂ / ethyl acetate / 4 h / 760 Torr / Ambient temperature

4: 6 N HCl / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydrogen; methanesulfonyl chloride; triethylamine; lithium hexamethyldisilazane; platinum(IV) oxide; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(98)00091-2

Reference yield:

: 144978-35-8,144978-12-1,251924-83-1
(S)-ethyl N-tert-butoxycarbonylpyroglutamate

: 207497-61-8
(2S,4S)-2-Amino-4-naphthalen-2-ylmethyl-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) lithium hexamethyldisilazide, 2.) BF₃*Et₂O / 1.) THF, -78 deg C, 1 h, 2.) THF, -78 deg C, 1 h

2: MsCl, Et₃N / CH₂Cl₂ / 48 h / Ambient temperature

3: H₂ / PtO₂ / ethyl acetate / 4 h / 760 Torr / Ambient temperature

4: 6 N HCl / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; hydrogen; methanesulfonyl chloride; triethylamine; lithium hexamethyldisilazane; platinum(IV) oxide; In dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(98)00091-2