Argpressin acetate

Base Information

• Chemical Name: Argpressin acetate
• CAS No.: 75499-44-4
• Molecular Formula: 2C₂H₄O₂*C₄₆H₆₅N₁₅O₁₂S₂
• Molecular Weight: 1204.35
• Mol file: 75499-44-4.mol

Synonyms:Argpressin acetate;Arginine Vasopressin Diacetate

Chemical Property of Argpressin acetate

Chemical Property:

• PSA: 549.33000
• LogP: 1.25190
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

HPLC>98% ^*data from raw suppliers

ArginineVasopressinDiacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An endogenous antidiuretic hormone in most mammalian species. Arginine Vasopressin Diacetate is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action. Arginine Vasopressin Diacetate is a peptidic V1a receptor agonist that produces vasoconstrictio n via V1aR-mediated vascular smooth muscle cell contraction and is being used to increase blood pressure in septic shock, a form of vasodilatory hypotension.

Technology Process of Argpressin acetate

There total 2 articles about Argpressin acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Tos-Cys(Bzl)-Tyr-Phe-Gln-Asn-Cys(Bzl)-Pro-Arg(Tos)-Gly-NH2 (30512-47-1) → <8-arginine>vasopressin (6512-97-6,75499-44-4,83968-48-3,129979-57-3)

Guidance literature:

With ammonia; dihydrogen peroxide; sodium; Yield given. Multistep reaction; 1) 30 sec, 2) 0.01 N AcOH/NH₃, pH 8.5;

DOI:10.1007/BF00598590

Reference yield:

Boc-Cys(Bzl)-Tyr-Phe-Gln-Asn-Cys(Bzl)-Pro-Arg(Tos)-Gly-NH2 (117922-51-7) → <8-arginine>vasopressin (6512-97-6,75499-44-4,83968-48-3,129979-57-3)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1007/BF00598590

upstream raw materials:

Boc-Cys(Bzl)-Tyr-Phe-Gln-Asn-Cys(Bzl)-Pro-Arg(Tos)-Gly-NH₂

Tos-Cys(Bzl)-Tyr-Phe-Gln-Asn-Cys(Bzl)-Pro-Arg(Tos)-Gly-NH₂