(R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

Base Information

Chemical Name:(R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL
CAS No.:203309-98-2
Molecular Formula:C₁₆H₁₉NO₂
Molecular Weight:257.332
Hs Code.:
Mol file:203309-98-2.mol

Synonyms:R-BPP;(R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL;(R)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

Suppliers and Price of (R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

Chemical Property:

Boiling Point:430.6±35.0 °C(Predicted)
PKA:13.78±0.20(Predicted)
PSA：41.49000
Density:1.117±0.06 g/cm3(Predicted)
LogP:2.60700

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

There total 1 articles about (R)-(+)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 71031-03-3,71031-02-2
(2R)-1,2-epoxy-3-phenoxypropane

: 100-46-9
benzylamine

: 203309-98-2,203309-99-3
(R)-1-Benzylamino-3-phenoxy-propan-2-ol

Guidance literature:: With β‐cyclodextrin;
DOI:10.1055/s-2006-933125

Reference yield:

: 203309-98-2,203309-99-3
(R)-1-Benzylamino-3-phenoxy-propan-2-ol

: (2S,3R)-1-Benzyl-3-phenoxymethyl-azetidine-2-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaHCO₃; NaI / dimethylformamide

2.1: SOCl₂ / CH₂Cl₂ / 2 h / Heating

2.2: 64 percent / dimethylformamide / 60 h / 65 °C

3.1: 75 percent / LiHMDS; HMPA / tetrahydrofuran / -78 - 0 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; thionyl chloride; sodium hydrogencarbonate; sodium iodide; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2006-933125

Reference yield:

: 203309-98-2,203309-99-3
(R)-1-Benzylamino-3-phenoxy-propan-2-ol

: 888494-28-8
[benzyl-(2-chloro-3-phenoxy-propyl)-amino]-acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaHCO₃; NaI / dimethylformamide

2.1: SOCl₂ / CH₂Cl₂ / 2 h / Heating

2.2: 64 percent / dimethylformamide / 60 h / 65 °C

With thionyl chloride; sodium hydrogencarbonate; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2006-933125