[2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester

Base Information

Chemical Name:[2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester
CAS No.:939757-25-2
Molecular Formula:C₁₃H₁₈N₂O₅
Molecular Weight:282.296
Hs Code.:
European Community (EC) Number:861-267-4
DSSTox Substance ID:DTXSID30585653
Mol file:939757-25-2.mol

Synonyms:939757-25-2;N-Boc-2-(4-nitrophenyl)-2-hydroxyethanamine;[2-hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester;tert-butyl N-[2-hydroxy-2-(4-nitrophenyl)ethyl]carbamate;Tert-butyl (2-hydroxy-2-(4-nitrophenyl)ethyl)carbamate;tert-Butyl [2-hydroxy-2-(4-nitrophenyl)ethyl]carbamate;(2-hydroxy-2-(4-nitrophenyl)ethyl)carbamic acid tert-butyl ester;[2-Hydroxy-2-(4-nitro-phenyl)-ethyl]-carbamic acid tert-butyl ester;SCHEMBL23728158;DTXSID30585653;CS-0458836;C78605;EN300-7548785;Z1496765182

Suppliers and Price of [2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[2-HYDROXY-2-(4-NITRO-PHENYL)ETHYL]CARBAMIC ACID-TERT-BUTYL ESTER 95.00%
5MG
$ 500.64

Acrotein
N-Boc-2-(4-nitrophenyl)-2-hydroxyethanamine 97%
1g
$ 293.33

Total 7 raw suppliers

Chemical Property of [2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester

Chemical Property:

Boiling Point:466.0±45.0 °C(Predicted)
PKA:11.99±0.46(Predicted)
PSA：104.38000
Density:1.242±0.06 g/cm3(Predicted)
LogP:3.06700
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:282.12157168
Heavy Atom Count:20
Complexity:340

Purity/Quality:

98% ^*data from raw suppliers

[2-HYDROXY-2-(4-NITRO-PHENYL)ETHYL]CARBAMIC ACID-TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(C1=CC=C(C=C1)[N+](=O)[O-])O

Technology Process of [2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester

There total 2 articles about [2-Hydroxy-2-(4-nitrophenyl)ethyl]carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (2-(4-nitrophenyl)-2-oxoethyl)carbamate

: 939757-25-2
tert-butyl (2-hydroxy-2-(4-nitrophenyl)ethyl)carbamate

Guidance literature:: With sodium tetrahydroborate; ethanol; at 0 - 20 ℃; for 1h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 939757-25-2
tert-butyl (2-hydroxy-2-(4-nitrophenyl)ethyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dichloromethane; water / 3 h / 20 °C

2: sodium tetrahydroborate; ethanol / 1 h / 0 - 20 °C

With sodium tetrahydroborate; ethanol; potassium carbonate; In dichloromethane; water;