p-2-Pyrrolidinylphenol

Base Information

• Chemical Name: p-2-Pyrrolidinylphenol
• CAS No.: 7167-71-7
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.219
• Mol file: 7167-71-7.mol

Synonyms:4-(2-Pyrrolidinyl)phenol;p-2-Pyrrolidinylphenol

Chemical Property of p-2-Pyrrolidinylphenol

Chemical Property:

• Melting Point: 166℃
• Boiling Point: 303℃
• Flash Point: 143℃
• Density: 1.107

Purity/Quality:

99% ^*data from raw suppliers

4-(Pyrrolidin-2-yl)phenol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of p-2-Pyrrolidinylphenol

There total 1 articles about p-2-Pyrrolidinylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-pyrrolidin-2-yl-phenol (7167-71-7,1217859-75-0)

Guidance literature:

2-<4-Hydroxy-phenyl>-Δ¹-pyrrolin, Me., NaBH4;

Reference yield: 60.0%

4-pyrrolidin-2-yl-phenol (7167-71-7,1217859-75-0) + phenyl (2-morpholino-5-(trifluoromethyl)phenyl)carbamate → 2-(4-hydroxyphenyl)-N-(2-morpholino-5-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide

Guidance literature:

With pyridine; Reflux; Inert atmosphere;

DOI:10.1021/acsmedchemlett.0c00311