[1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-

Base Information

Chemical Name:[1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-
CAS No.:335259-27-3
Molecular Formula:C12H11FN2
Molecular Weight:202.231
Hs Code.:

Synonyms:[1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-;335259-27-3;SCHEMBL4048618;4'-fluorobiphenyl-3,4-diamine;4'-fluoro-biphenyl-3,4-diamine;VKBYMIFDJNVPAE-UHFFFAOYSA-N;4-(4-fluorophenyl)benzene-1,2-diamine;4'-Fluoro-[1,1'-biphenyl]-3,4-diamine;A1-35279

Suppliers and Price of [1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-

Chemical Property:

PSA：52.04000
LogP:3.81950
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:202.09062652
Heavy Atom Count:15
Complexity:202

Purity/Quality:: 97-99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=C(C=C2)N)N)F

Technology Process of [1,1'-Biphenyl]-3,4-diamine, 4'-fluoro-

There total 2 articles about [1,1'-Biphenyl]-3,4-diamine, 4'-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5228-61-5
5-bromo-2-nitroaniline

: 335259-27-3
4’-fluoro-[1,1’-biphenyl]-3,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate

2: palladium on activated charcoal; ammonium formate / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium on activated charcoal; ammonium formate; potassium carbonate; 1: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmcl.2013.07.001

Reference yield:

: 20691-72-9
4-iodo-2-nitroaniline

: 335259-27-3
4’-fluoro-[1,1’-biphenyl]-3,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: palladium dichloride; sodium hydroxide / methanol; water / 26 h / 20 °C / Reflux

2: sodium tetrahydroborate; palladium 10% on activated carbon / methanol / 27 h / 20 °C

With sodium tetrahydroborate; palladium 10% on activated carbon; sodium hydroxide; palladium dichloride; In methanol; water;
DOI:10.1002/ejoc.201900463