L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL

Base Information

• Chemical Name: L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL
• CAS No.: 129170-43-0
• Molecular Formula: C11H18N2O2
• Molecular Weight: 210.27
• Mol file: 129170-43-0.mol

Synonyms:L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL

Chemical Property of L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL

Chemical Property:

• PSA: 69.72000
• LogP: 0.80590

Purity/Quality:

98% ^*data from raw suppliers

L-(+)-Threo-2-(N,N-dimethylamino)-1-(4-aminophenyl)-1,3-propanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL

There total 1 articles about L-(+)-THREO-2-(N,N-DIMETHYLAMINO)-1-(4-AMINOPHENYL)-1,3-PROPANEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

threo-(1S,2S)-2-(dimethylamino)-1-(4-nitrophenyl)-1,3-propanediol (18867-44-2) → (+)-threo-1-(4-aminophenyl)-2-dimethylamino-1,3-propanediol (129170-43-0,131392-15-9)

Guidance literature:

With hydrazine hydrate; RaNi; In ethanol; for 6h; Heating;

Reference yield: 79.0%

4-nitrobenzaldehdye (555-16-8) + (+)-threo-1-(4-aminophenyl)-2-dimethylamino-1,3-propanediol (129170-43-0,131392-15-9) → (1S,2S)-2-Dimethylamino-1-(4-{[1-(4-nitro-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol (111650-36-3)

Guidance literature:

In ethanol; for 5h; Heating;

Reference yield: 78.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + (+)-threo-1-(4-aminophenyl)-2-dimethylamino-1,3-propanediol (129170-43-0,131392-15-9) → (1S,2S)-2-Dimethylamino-1-(4-{[1-(4-hydroxy-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol (111650-37-4)

Guidance literature:

In ethanol; for 5h; Heating;

upstream raw materials:

threo-(1S,2S)-2-(dimethylamino)-1-(4-nitrophenyl)-1,3-propanediol

Downstream raw materials:

(1S,2S)-2-Dimethylamino-1-(4-{[1-(3-nitro-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol

(1S,2S)-2-Dimethylamino-1-(4-{[1-(4-nitro-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol

(1S,2S)-2-Dimethylamino-1-(4-{[1-phenyl-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol

(1S,2S)-2-Dimethylamino-1-(4-{[1-(4-hydroxy-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-propane-1,3-diol

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