N-(4-aminophenyl)-5-methylfuran-2-carboxamide

Base Information

Chemical Name:N-(4-aminophenyl)-5-methylfuran-2-carboxamide
CAS No.:727387-19-1
Molecular Formula:C₁₂H₁₂N₂O₂
Molecular Weight:216.239
Hs Code.:
DSSTox Substance ID:DTXSID60589563
Wikidata:Q82483012

Synonyms:727387-19-1;N-(4-AMINOPHENYL)-5-METHYL-2-FURAMIDE;N-(4-aminophenyl)-5-methylfuran-2-carboxamide;CHEMBRDG-BB 5925667;SCHEMBL7777752;DTXSID60589563;MFCD00448324;AKOS003240781;BS-36235;DB-119660;CS-0331223

Suppliers and Price of N-(4-aminophenyl)-5-methylfuran-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(4-aminophenyl)-5-methylfuran-2-carboxamide

Chemical Property:

Vapor Pressure:0.000607mmHg at 25°C
Boiling Point:310.2°C at 760 mmHg
Flash Point:141.4°C
Density:1.274g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:216.089877630
Heavy Atom Count:16
Complexity:249

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(O1)C(=O)NC2=CC=C(C=C2)N

Technology Process of N-(4-aminophenyl)-5-methylfuran-2-carboxamide

There total 2 articles about N-(4-aminophenyl)-5-methylfuran-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-50-3
1,4-phenylenediamine

: 727387-19-1
5-Methyl-furan-2-carboxylic acid (4-amino-phenyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / N,N-dimethyl-formamide / 6 h / 20 °C

2: triethylamine / dichloromethane / 3 h / 0 - 20 °C

3: triethylamine / dichloromethane / 4 h / 0 - 20 °C

With triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1111/cbdd.12529

Reference yield:

: 71026-66-9
N-(tert-butoxycarbonyl)-1,4-phenylenediamine

: 727387-19-1
5-Methyl-furan-2-carboxylic acid (4-amino-phenyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3 h / 0 - 20 °C

2: triethylamine / dichloromethane / 4 h / 0 - 20 °C

With triethylamine; In dichloromethane;
DOI:10.1111/cbdd.12529

Reference yield:

: 727387-19-1
5-Methyl-furan-2-carboxylic acid (4-amino-phenyl)-amide

: N-(4-(4-hydrazinyl-4-oxobutanamido)phenyl)-5-methylfuran-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.5 h / 165 °C / Molecular sieve; Microwave irradiation

2: hydrazine hydrate / ethanol / 4 h / Reflux

With hydrazine hydrate; In tetrahydrofuran; ethanol;
DOI:10.1111/cbdd.12529