5-Bromo-7-chloroindoline

Base Information

Chemical Name:5-Bromo-7-chloroindoline
CAS No.:221024-31-3
Molecular Formula:C8H7BrClN
Molecular Weight:232.507
Hs Code.:
DSSTox Substance ID:DTXSID701283703
Mol file:221024-31-3.mol

Synonyms:5-Bromo-7-chloroindoline;221024-31-3;5-BROMO-7-CHLORO-2,3-DIHYDRO-1H-INDOLE;5-bromo-7-chloro-indoline;SCHEMBL4869350;MVNYXXSOOZHUAR-UHFFFAOYSA-N;DTXSID701283703;WIA02431;MFCD09735925;AKOS009133095;SB35514;CS-0141420;EN300-1145541

Suppliers and Price of 5-Bromo-7-chloroindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
5-Bromo-7-chloro-2,3-dihydro-1H-indole 96%
500mg
$ 549.00

Crysdot
5-Bromo-7-chloroindoline 95+%
1g
$ 1081.00

Chemenu
5-bromo-7-chloroindoline 95%
1g
$ 1018.00

Alichem
5-Bromo-7-chloroindoline
25g
$ 2626.40

Alichem
5-Bromo-7-chloroindoline
10g
$ 1575.84

Alichem
5-Bromo-7-chloroindoline
5g
$ 1278.36

Total 7 raw suppliers

Chemical Property of 5-Bromo-7-chloroindoline

Chemical Property:

Boiling Point:309.1±42.0 °C(Predicted)
PKA:2.57±0.20(Predicted)
PSA：12.03000
Density:1.629±0.06 g/cm3(Predicted)
LogP:3.20850
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:230.94504
Heavy Atom Count:11
Complexity:153

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-7-chloro-2,3-dihydro-1H-indole 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CNC2=C1C=C(C=C2Cl)Br

Technology Process of 5-Bromo-7-chloroindoline

There total 3 articles about 5-Bromo-7-chloroindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 221024-29-9
1-acetyl-5-bromo-7-chloro-indoline

: 221024-31-3
5-bromo-7-chloro-indoline

Guidance literature:: With lithium hydroxide; In methanol; water; for 12h; Heating;
DOI:10.1021/jm010523x

Reference yield:

: 22190-38-1
5-bromo-N-acetylindoline

: 221024-31-3
5-bromo-7-chloro-indoline

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / N-chlorosuccinimide / acetonitrile / 24 h / Heating

2: 99 percent / LiOH / methanol; H₂O / 12 h / Heating

With lithium hydroxide; N-chloro-succinimide; In methanol; water; acetonitrile;
DOI:10.1021/jm010523x

Reference yield:

: 22190-33-6
5-bromoindoline

: 221024-31-3
5-bromo-7-chloro-indoline

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / dichloromethane / 4 h / 0 - 20 °C

2: N-chloro-succinimide / acetonitrile / 18 h / 70 °C

3: water; lithium hydroxide monohydrate / methanol / 18 h / 70 °C

With dmap; N-chloro-succinimide; lithium hydroxide monohydrate; water; triethylamine; In methanol; dichloromethane; acetonitrile;