Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-

Base Information

Chemical Name:Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-
CAS No.:128425-96-7
Molecular Formula:C18H23NO4
Molecular Weight:317.37952
Hs Code.:
Mol file:128425-96-7.mol

Synonyms:Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-

Suppliers and Price of Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-

Chemical Property:

PSA：48.00000
LogP:3.39400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy-

There total 4 articles about Spiro[cyclohexane-1,1(5H)-[3H]oxazolo[4,3-a]isoquinolin]-3-one, 6,10b-dihydro-8,9-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 128425-94-5
1,5,6,10b-Tetrahydro-10b-hydroxy-8,9-dimethoxy-1,1-pentamethylene-3H-oxazolo<4,3-a>isoquinolin-3-one

: 128425-96-7
1,5,6,10b-Tetrahydro-8,9-dimethoxy-1,1-pentamethylene-3H-oxazolo<4,3-a>isoquinolin-3-one

Guidance literature:: With sodium cyanoborohydride; acetic acid;

Reference yield:

: 69743-45-9
1-cyclohexyl-3,4-dihydro-6,7-dimethoxyisoquinoline

: 128425-96-7
1,5,6,10b-Tetrahydro-8,9-dimethoxy-1,1-pentamethylene-3H-oxazolo<4,3-a>isoquinolin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / Di-isopropylethylamine / CH₂Cl₂ / 18 h

2: 80 percent / Pb(OAc)4, glac. acetic acid / 2.5 h

3: 92 percent / sodium cyanoborohydride, glacial acetic acid

With lead(IV) acetate; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;

Reference yield:

: 128425-95-6
Methyl 1-Cyclohexylidene-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

: 128425-96-7
1,5,6,10b-Tetrahydro-8,9-dimethoxy-1,1-pentamethylene-3H-oxazolo<4,3-a>isoquinolin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / Pb(OAc)4, glac. acetic acid / 2.5 h

2: 92 percent / sodium cyanoborohydride, glacial acetic acid

With lead(IV) acetate; sodium cyanoborohydride; acetic acid;