2-(Pyridin-2-ylamino)quinolin-8-ol

Base Information

Chemical Name:2-(Pyridin-2-ylamino)quinolin-8-ol
CAS No.:70125-23-4
Molecular Formula:C₁₄H₁₁N₃O
Molecular Weight:237.261
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90362503
Wikidata:Q82145637
ChEMBL ID:CHEMBL530049
Mol file:70125-23-4.mol

Synonyms:2-(pyridin-2-ylamino)quinolin-8-ol;70125-23-4;2-(2-PYRIDINYLAMINO)-8-QUINOLINOL;MLS000105600;TCMDC-125567;GNF-Pf-2460;SMR000102480;ChemDiv2_000177;Oprea1_423978;CHEMBL530049;SCHEMBL8342587;BDBM53590;cid_1380879;DTXSID90362503;2-(2-pyridylamino)quinolin-8-ol;CHEMBRDG-BB 5175087;HMS1369I01;HMS2400M13;MFCD00168938;2-(2-pyridylamino)-8-hydroxyquinoline;CCG-103027;BS-36304;FT-0769948;AB00074873-01;SR-01000388298;SR-01000388298-1

Suppliers and Price of 2-(Pyridin-2-ylamino)quinolin-8-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(Pyridin-2-ylamino)quinolin-8-ol 95+%
1g
$ 698.00

Chemenu
2-(pyridin-2-ylamino)quinolin-8-ol 95%
1g
$ 660.00

ChemBridge Corporation
2-(2-pyridinylamino)-8-quinolinol 95%
1 g
$ 300.00

American Custom Chemicals Corporation
2-(2-PYRIDINYLAMINO)-8-QUINOLINOL 95.00%
5MG
$ 504.90

Alichem
2-(Pyridin-2-ylamino)quinolin-8-ol
1g
$ 602.08

Total 7 raw suppliers

Chemical Property of 2-(Pyridin-2-ylamino)quinolin-8-ol

Chemical Property:

Vapor Pressure:7.29E-09mmHg at 25°C
Boiling Point:454.1°C at 760 mmHg
Flash Point:228.4°C
PSA：58.04000
Density:1.359g/cm³
LogP:3.15200
Storage Temp.:2-8°C
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:237.090211983
Heavy Atom Count:18
Complexity:274

Purity/Quality:

98% ^*data from raw suppliers

2-(Pyridin-2-ylamino)quinolin-8-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)NC2=NC3=C(C=CC=C3O)C=C2

Technology Process of 2-(Pyridin-2-ylamino)quinolin-8-ol

There total 5 articles about 2-(Pyridin-2-ylamino)quinolin-8-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.4%

: 8-methoxy-N-(pyridin-2-yl)quinolin-2-amine

: 70125-23-4
2-(pyridin-2-ylamino)-quinolin-8-ol

Guidance literature:: With boron tribromide; In dichloromethane; at -40 ℃; Inert atmosphere; Reflux;
DOI:10.1016/j.bmc.2016.03.016

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 70125-23-4
2-(pyridin-2-ylamino)-quinolin-8-ol

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetone / 0.5 h / 20 °C

1.2: 8 h / 60 °C

2.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 0 - 20 °C

3.1: dichloromethane; water / 0.5 h

3.2: 2 h / 20 °C / Alkaline conditions

4.1: hydrogenchloride / water / 15 h / 100 °C

5.1: boron tribromide / dichloromethane / -40 °C / Inert atmosphere; Reflux

With hydrogenchloride; boron tribromide; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; chloroform; water; acetone;
DOI:10.1016/j.bmc.2016.03.016

Reference yield:

: 22614-90-0
8--methoxyquinoline N--oxide

: 70125-23-4
2-(pyridin-2-ylamino)-quinolin-8-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: dichloromethane; water / 0.5 h

1.2: 2 h / 20 °C / Alkaline conditions

2.1: hydrogenchloride / water / 15 h / 100 °C

3.1: boron tribromide / dichloromethane / -40 °C / Inert atmosphere; Reflux

With hydrogenchloride; boron tribromide; In dichloromethane; water;
DOI:10.1016/j.bmc.2016.03.016