4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine

Base Information

• Chemical Name: 4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine
• CAS No.: 118121-89-4
• Molecular Formula: C8H12FN5O
• Molecular Weight: 213.21
• Hs Code.: 2933599590
• DSSTox Substance ID: DTXSID60350311
• Wikidata: Q82126171
• ChEMBL ID: CHEMBL3794495
• Mol file: 118121-89-4.mol

Synonyms:118121-89-4;4-(5-fluoro-2-hydrazinylpyrimidin-4-yl)morpholine;4-(5-Fluoro-2-hydrazinopyrimidin-4-yl)morpholine;(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)hydrazine;CHEMBRDG-BB 4021967;Oprea1_430479;Oprea1_751095;SCHEMBL3579929;CHEMBL3794495;DTXSID60350311;MFCD00181489;STL380121;AKOS000421051;WAY-299582;BS-36807;CS-0441980;4-(5-Fluoro-2-hydrazino-4-pyrimidinyl)morpholine;A893214

Chemical Property of 4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine

Chemical Property:

• Vapor Pressure: 1.2E-07mmHg at 25°C
• Boiling Point: 431.5°C at 760 mmHg
• Flash Point: 214.7°C
• PSA: 76.30000
• Density: 1.421g/cm³
• LogP: 0.57620
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 213.10258819
• Heavy Atom Count: 15
• Complexity: 202

Purity/Quality:

97% ^*data from raw suppliers

4-(5-Fluoro-2-hydrazinopyrimidin-4-yl)morpholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C2=NC(=NC=C2F)NN

Technology Process of 4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine

There total 1 articles about 4-(5-Fluoro-2-hydrazinylpyrimidin-4-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-chloro-5-fluoro-pyrimidin-4-yl)morpholine (31646-53-4) → 4-(5-fluoro-2-hydrazinylpyrimidin-4-yl)morpholine (118121-89-4)

Guidance literature:

With hydrazine; for 2h; Heating / reflux;

Reference yield:

4-(5-fluoro-2-hydrazinylpyrimidin-4-yl)morpholine (118121-89-4) + C14H9F3N2O2 (1044210-05-0) → C22H19F4N7O2 (932019-65-3)

Guidance literature:

In dichloromethane; at 20 ℃;

Reference yield:

4-(5-fluoro-2-hydrazinylpyrimidin-4-yl)morpholine (118121-89-4) + C14H9F3N2O2 (1044210-17-4) → C22H19F4N7O2 (932019-64-2)

Guidance literature:

In dichloromethane; at 20 ℃;

upstream raw materials:

4-(2-chloro-5-fluoro-pyrimidin-4-yl)morpholine

Downstream raw materials:

C₂₃H₂₄FN₇O₃

C₂₆H₂₄FN₇O₂

C₂₃H₂₇FN₈O₂

C₂₆H₂₄FN₇O₂