Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate

Base Information

Chemical Name:Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate
CAS No.:216867-38-8
Molecular Formula:C₁₁H₁₀N₂O₂S
Molecular Weight:234.279
Hs Code.:2934100090
Mol file:216867-38-8.mol

Synonyms:Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate;4-Pyridin-4-Yl-Thiazole-2-Carboxylic Acid Ethyl Ester Hydrobromate

Suppliers and Price of Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl4-(pyridin-4-yl)thiazole-2-carboxylate 95+%
5g
$ 523.00

Chemenu
Ethyl4-(pyridin-4-yl)thiazole-2-carboxylate 95%
5g
$ 489.00

Alichem
Ethyl4-(pyridin-4-yl)thiazole-2-carboxylate
1g
$ 254.43

Alichem
Ethyl4-(pyridin-4-yl)thiazole-2-carboxylate
5g
$ 818.32

AK Scientific
Ethyl4-(4-pyridyl)-2-thiazolecarboxylate
5g
$ 766.00

Total 7 raw suppliers

Chemical Property of Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate

Chemical Property:

PSA：80.32000
LogP:2.38180

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-(pyridin-4-yl)thiazole-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate

There total 2 articles about Ethyl 4-(4-Pyridyl)-2-thiazolecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 16982-21-1
ethyl 2-amino-2-thioxoacetate

: 5349-17-7
4-bromoacetylpyridine hydrobromide

: 216867-38-8
ethyl 4-(4-pyridyl)thiazole-2-carboxylate

Guidance literature:: In ethanol; for 4h; Reflux;
DOI:10.1134/S1070363219120314

Reference yield:

: 1122-54-9
methyl (4-pyridyl) ketone

: 216867-38-8
ethyl 4-(4-pyridyl)thiazole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; bromine; hydrogen bromide / water / 0.33 h / 90 °C

2: ethanol / 16 h / Reflux

With hydrogen bromide; bromine; acetic acid; In ethanol; water;
DOI:10.1021/acs.jmedchem.7b00443

Reference yield:

: 216867-38-8
ethyl 4-(4-pyridyl)thiazole-2-carboxylate

: 59020-47-2
4-(pyridin-4-yl)thiazole-2-carboxylic acid

Guidance literature:: ethyl 4-(pyridin-4-yl)thiazole-2-carboxylate; With sodium hydroxide; In etanol; at 20 ℃; for 2h;

With hydrogenchloride; In water;