1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol

Base Information

Chemical Name:1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol
CAS No.:119874-35-0
Molecular Formula:C₂₈H₃₈O₆Si
Molecular Weight:498.692
Hs Code.:
DSSTox Substance ID:DTXSID90435180
Nikkaji Number:J1.096.305B
Wikidata:Q82249920
Mol file:119874-35-0.mol

Synonyms:119874-35-0;1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol;(1R,3S,7R,9R)-8-[Tert-butyl(diphenyl)silyl]oxy-5,5,11,11-tetramethyl-4,6,10,12-tetraoxatricyclo[7.3.0.03,7]dodecan-2-ol;DTXSID90435180;SFPIFESXSAQLCS-NEGOCDRDSA-N;119943-93-0;E10190;1-O-(tert-Butyldiphenylsilyl)-2-O,3-O:5-O,6-O-diisopropylidene-D-myo-inositol;(3AR,4S,4aS,7aR,8S,8aR)-8-((tert-butyldiphenylsilyl)oxy)-2,2,6,6-tetramethylhexahydrobenzo[1,2-d:4,5-d']bis([1,3]dioxole)-4-ol

Suppliers and Price of 1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-O-[(t-Butyldiphenylsilyl]-1,2:4,5-bis-O-(1-methylethylidene)D,L-myo-Inositol
10mg
$ 120.00

Medical Isotopes, Inc.
3-O-[(t-Butyldiphenylsilyl]-1,2:4,5-bis-O-(1-methylethylidene)-D,L-myo-inositol
50 mg
$ 1720.00

Medical Isotopes, Inc.
3-O-[(t-Butyldiphenylsilyl]-1,2:4,5-bis-O-(1-methylethylidene)-D,L-myo-inositol
10 mg
$ 840.00

Total 2 raw suppliers

Chemical Property of 1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol

Chemical Property:

Melting Point:52-54°C
PSA：66.38000
LogP:3.34630
Solubility.:Chloroform, Dichloromethane, Methanol
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:498.24376546
Heavy Atom Count:35
Complexity:701

Purity/Quality:

95% ^*data from raw suppliers

3-O-[(t-Butyldiphenylsilyl]-1,2:4,5-bis-O-(1-methylethylidene)D,L-myo-Inositol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OC2C(C3C(C(C2O1)O[Si](C4=CC=CC=C4)(C5=CC=CC=C5)C(C)(C)C)OC(O3)(C)C)O)C
Isomeric SMILES:CC1(O[C@@H]2[C@@H](O1)C([C@H]3[C@@H](C2O)OC(O3)(C)C)O[Si](C4=CC=CC=C4)(C5=CC=CC=C5)C(C)(C)C)C

Technology Process of 1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol

There total 1 articles about 1-O-(tert-Butyldiphenylsilyl)-2,3:5,6-di-O-isoproylidene-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 51548-88-0,96039-15-5,98974-89-1,128110-25-8
(+/-)-1,2:4,5-di-O-isopropylidene-myo-inositol

: 58479-61-1
tert-butylchlorodiphenylsilane

: 119874-35-0,119943-93-0,124648-22-2
1⁽³⁾-O-(tert-butyldiphenylsilyl)-2,3⁽¹⁾:5,6⁽⁴⁾-di-O-isopropylidene-D-myo-inositol

Guidance literature:: With 1H-imidazole; In pyridine; at -20 ℃; for 48h;
DOI:10.1016/S0009-3084(97)00069-8

Reference yield: 66.0%

: 119874-35-0,119943-93-0,124648-22-2
1⁽³⁾-O-(tert-butyldiphenylsilyl)-2,3⁽¹⁾:5,6⁽⁴⁾-di-O-isopropylidene-D-myo-inositol

: 109-92-2,25104-37-4
ethyl vinyl ether

: tert-Butyl-[(3aR,4S,4aR,7aS,8S,8aR)-8-(1-ethoxy-ethoxy)-2,2,6,6-tetramethyl-hexahydro-benzo[1,2-d;4,5-d']bis[1,3]dioxol-4-yloxy]-diphenyl-silane

Guidance literature:: With pyridinium p-toluenesulfonate; In dichloromethane; for 0.5h; Ambient temperature;
DOI:10.1016/S0009-3084(97)00069-8

Reference yield:

: 119874-35-0,119943-93-0,124648-22-2
1⁽³⁾-O-(tert-butyldiphenylsilyl)-2,3⁽¹⁾:5,6⁽⁴⁾-di-O-isopropylidene-D-myo-inositol

: 1⁽³⁾-O-n-propylphosphoryl-D-myo-inositol

Guidance literature:: Multi-step reaction with 4 steps

1: pyridinium 4-toluenesulfonate / CH₂Cl₂ / 1 h

2: tetrabutylammonium fluoride / tetrahydrofuran / 16 h / Ambient temperature

3: 33 percent / triisopropylbenzenesulphonyl chloride, pyridine / 5 h / Ambient temperature

4: 1.) H₂, 50percent aq. EtOH / 1.) PtO₂ / 1.) EtOH, 3 atm, 2 h

With pyridine; ethanol; triisopropylbenzenesulphonyl chloride; tetrabutyl ammonium fluoride; hydrogen; pyridinium p-toluenesulfonate; platinum(IV) oxide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/0223-5234(94)90146-5