Iotalamic acid

Base Information

• Chemical Name: Iotalamic acid
• CAS No.: 2276-90-6
• Deprecated CAS: 5551-54-2
• Molecular Formula: C11H9 I3 N2 O4
• Molecular Weight: 613.917
• Hs Code.: 2924296000
• European Community (EC) Number: 218-897-4
• NSC Number: 759891
• UNII: 16CHD79MIX
• DSSTox Substance ID: DTXSID5023164
• Nikkaji Number: J7.384I
• Wikipedia: Iotalamic_acid
• Wikidata: Q6064129
• NCI Thesaurus Code: C61792
• RXCUI: 1546451
• Metabolomics Workbench ID: 143604
• ChEMBL ID: CHEMBL1201300
• Mol file: 2276-90-6.mol

Synonyms:Acid, Iotalamic;Acid, Iothalamic;Acid, Methalamic;Angio Conray;Angio-Conray;AngioConray;Conray 420;Iodothalamate;Iotalamic Acid;Iothalamate;Iothalamate, Sodium;Iothalamic Acid;Iothalamic Acid, Calcium (2:1) Salt;Iothalamic Acid, Monosilver (1+) Salt;Iothalamic Acid, Monosodium Salt;Iothalamic Acid, Monosodium Salt, Dimer;Lopamidol;Methalamic Acid;Sodium Iothalamate

Chemical Property of Iotalamic acid

Chemical Property:

• Appearance/Colour: off-white to white powder
• Melting Point: 285 C
• Boiling Point: 520.2 °C at 760 mmHg
• PKA: 0.78±0.10(Predicted)
• Flash Point: 268.4 °C
• PSA: 95.50000
• Density: 2.54 g/cm³
• LogP: 2.98050
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 613.7696
• Heavy Atom Count: 20
• Complexity: 421

Purity/Quality:

99.9% ^*data from raw suppliers

Iothalamic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): UN NO.
• Hazard Codes: UN NO.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
• Uses: Iothalamic Acid is used as a contrast medium in diagnostic radiology. Iothalamic Acid displayed the same level of nephrotoxicity against rat and human renal epithelial cells as conventional ionic cont rast medioum. Iothalamic Acid is used as a contrast medium in diagnostic radiology. Iothalamic Acid displayed the same level of nephrotoxicity against rat and human renal epithelial cells as conventional ionic contrast medioum.
• Therapeutic Function: Diagnostic aid (radiopaque medium)

Technology Process of Iotalamic acid

There total 1 articles about Iotalamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ iothalamic acid (2276-90-6)

Guidance literature:

1) 2,4,6-Triiod-5-amino-isophthalsaeure-mono-methylamid, Acetylchlorid in Ggw. v. Dimethylacetamid (1.5h, Raumtemp.);

DOI:10.1021/jm00337a005

Refernces

• 1、 -. "Iodinated aromatic compounds". . . Retrieved 2008/06/13.
• 2、 -. "Iodinated benzoyl acetals and ketals for x-ray imaging". . . Retrieved 2008/06/13.