1-Boc-3-(1-hydroxyethyl)-azetidine

Base Information

Chemical Name:1-Boc-3-(1-hydroxyethyl)-azetidine
CAS No.:1138331-90-4
Molecular Formula:C10H19NO3
Molecular Weight:201.26276
Hs Code.:2933998090
Mol file:1138331-90-4.mol

Synonyms:1-Boc-3-(1-hydroxyethyl)-azetidine;tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

Suppliers and Price of 1-Boc-3-(1-hydroxyethyl)-azetidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-Boc-3-(1-hydroxyethyl)azetidine
1 g
$ 1277.00

Crysdot
tert-Butyl3-(1-hydroxyethyl)azetidine-1-carboxylate 95+%
1g
$ 518.00

Apolloscientific
1-Boc-3-(1-hydroxyethyl)-azetidine
1g
$ 1078.00

Acrotein
1-Boc-3-(1-hydroxyethyl)-azetidine 97%
1g
$ 330.00

ACHEMBLOCK
1-Boc-3-(1-hydroxyethyl)-azetidine 95%
1G
$ 380.00

Total 7 raw suppliers

Chemical Property of 1-Boc-3-(1-hydroxyethyl)-azetidine

Chemical Property:

PSA：49.77000
LogP:1.17200

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-3-(1-hydroxyethyl)azetidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Boc-3-(1-hydroxyethyl)-azetidine

There total 3 articles about 1-Boc-3-(1-hydroxyethyl)-azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 870089-49-9
tert‐butyl 3‐acetylazetidine‐1‐carboxylate

: 1138331-90-4
tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;

Reference yield:

: 142253-55-2
1-(t-butyloxycarbonyl)-azetidine-3-carboxylic acid

: 1138331-90-4
tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 16 h / 20 °C

2.1: tetrahydrofuran; diethyl ether / 16 h / -78 - 20 °C

3.1: sodium tetrahydroborate / methanol / 2 h / 20 °C

With sodium tetrahydroborate; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide;

Reference yield:

: 820971-67-3
tert-butyl 3-{[methoxy(methyl)amino]carbonyl}azetidine-1-carboxylate

: 1138331-90-4
tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 16 h / -78 - 20 °C

2: sodium tetrahydroborate / methanol / 2 h / 20 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol; diethyl ether;