1,2-dimethyl-1H-imidazole-5-carboxylicacid

Base Information

• Chemical Name: 1,2-dimethyl-1H-imidazole-5-carboxylicacid
• CAS No.: 122222-09-7
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.142
• Hs Code.: 2933290090
• Mol file: 122222-09-7.mol

Synonyms:1,2-dimethyl-1H-imidazole-5-carboxylicacid;2,3-diMethyliMidazole-4-carboxylic acid

Chemical Property of 1,2-dimethyl-1H-imidazole-5-carboxylicacid

Chemical Property:

• PSA: 55.12000
• LogP: 0.42670
• Storage Temp.: 2-8°C

Purity/Quality:

99%min. ^*data from raw suppliers

1,2-Dimethyl-1H-imidazole-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-dimethyl-1H-imidazole-5-carboxylicacid

There total 4 articles about 1,2-dimethyl-1H-imidazole-5-carboxylicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

→ 1,2-dimethyl-1H-imidazole-5-carboxylic acid (122222-09-7) + 1,2-Dimethylimidazol-4-carbonsaeure-methylester (122222-10-0)

Guidance literature:

Reference yield:

1,2-dimethyl-1H-imidazole-4,5-dicarboxylic acid → 1,2-dimethyl-1H-imidazole-5-carboxylic acid (122222-09-7)

Guidance literature:

With acetic anhydride; at 100 ℃; for 16h;

Reference yield:

2-methyl-1H-imidazole-4,5-dicarbonitrile (40056-53-9) → 1,2-dimethyl-1H-imidazole-5-carboxylic acid (122222-09-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / water / 6 h / 55 °C

2: sodium hydroxide / water / 6 h / 100 °C

3: acetic anhydride / 16 h / 100 °C

With acetic anhydride; sodium hydrogencarbonate; sodium hydroxide; In water;

upstream raw materials:

2-methyl-1H-imidazole-4,5-dicarbonitrile

1,2-dimethyl-1H-imidazole-4,5-dicarbonitrile

Refernces

• 1、 -. "Preparation of 1-alkylimidazoles". . . Retrieved 2008/06/13.