ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE
• CAS No.: 31310-19-7
• Molecular Formula: C12H13NO2S
• Molecular Weight: 235.307
• Hs Code.: 2934999090
• Mol file: 31310-19-7.mol

Synonyms:ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE;BUTTPARK 37\04-22

Chemical Property of ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE

Chemical Property:

• Boiling Point: 396.0±37.0 °C(Predicted)
• PKA: 3.81±0.10(Predicted)
• PSA: 80.56000
• Density: 1.265±0.06 g/cm3(Predicted)
• LogP: 3.54980

Purity/Quality:

97% ^*data from raw suppliers

Ethyl5-Amino-3-methylbenzo[b]thiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE

There total 3 articles about ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-methyl-5-nitrobenzo[b]thiophene-2-carboxylate (17514-60-2) → 5-amino-3-methyl-benzo[b]thiophene-2-carboxylic acid ethyl ester (31310-19-7)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.ejmech.2017.05.042

Reference yield:

2'-chloro-5'-nitroacetophenone (23082-50-0) → 5-amino-3-methyl-benzo[b]thiophene-2-carboxylic acid ethyl ester (31310-19-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 20 °C / Reflux

2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 20 °C

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In tetrahydrofuran; ethanol;

DOI:10.1016/j.ejmech.2017.05.042

Reference yield:

→ 5-amino-3-methyl-benzo[b]thiophene-2-carboxylic acid ethyl ester (31310-19-7)

Guidance literature:

entspr. Nitroverb., Raney-Ni, Hydrazinhydrat;

upstream raw materials:

2'-chloro-5'-nitroacetophenone

ethyl 3-methyl-5-nitrobenzo[b]thiophene-2-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 31310-19-7 ETHYL 5-AMINO-3-METHYLBENZO[B]THIOPHENE-2-CARBOXYLATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send