1,3-Diaminoisoquinoline

Base Information

• Chemical Name: 1,3-Diaminoisoquinoline
• CAS No.: 1955-65-3
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.191
• Mol file: 1955-65-3.mol

Synonyms:1,3-Diaminoisoquinoline;1,3-isoquinolinediamine

Chemical Property of 1,3-Diaminoisoquinoline

Chemical Property:

• PSA: 64.93000
• LogP: 2.56160

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,3-Isoquinolinediamine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Diaminoisoquinoline

There total 2 articles about 1,3-Diaminoisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1-amino-3-formamidoisoquinoline (87606-66-4) → 1,3-diaminoisoquinoline (1955-65-3)

Guidance literature:

With sodium hydroxide; In ethanol; for 1h; Heating;

Reference yield:

→ 1,3-diaminoisoquinoline (1955-65-3)

Guidance literature:

2-Cyan-benzylcyanid, Me., NH3(fl.);

Reference yield:

4-aminobenzamidine dihydrochloride (2498-50-2) + 1,3-diaminoisoquinoline (1955-65-3) → (E)-4-((1,3-diaminoisoquinolin-4-yl)diazenyl)benzimidamide

Guidance literature:

4-aminobenzamidine dihydrochloride; With hydrogenchloride; In water; at 0 ℃; for 0.25h;

With sodium nitrite; In water; for 0.25h; Cooling;

1,3-diaminoisoquinoline; Further stages;

DOI:10.1021/acsmedchemlett.6b00468

upstream raw materials:

1-amino-3-formamidoisoquinoline

Refernces