2-aMino-4-chloro-6-cyclopropylpyriMidine

Base Information

Chemical Name:2-aMino-4-chloro-6-cyclopropylpyriMidine
CAS No.:21573-09-1
Molecular Formula:C7H8ClN3
Molecular Weight:169.614
Hs Code.:
Mol file:21573-09-1.mol

Synonyms:2-aMino-4-chloro-6-cyclopropylpyriMidine;4-chloro-6-cyclopropyl-pyriMidin-2-ylaMine

Suppliers and Price of 2-aMino-4-chloro-6-cyclopropylpyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
4-Chloro-6-cyclopropylpyrimidin-2-amine 95%
1g
$ 636.00

Alichem
4-Chloro-6-cyclopropylpyrimidin-2-amine
1g
$ 780.44

AK Scientific
4-Chloro-6-cyclopropylpyrimidin-2-amine
1g
$ 831.00

Total 8 raw suppliers

Chemical Property of 2-aMino-4-chloro-6-cyclopropylpyriMidine

Chemical Property:

PSA：52.53000
LogP:1.51970

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-6-cyclopropylpyrimidin-2-amine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-aMino-4-chloro-6-cyclopropylpyriMidine

There total 5 articles about 2-aMino-4-chloro-6-cyclopropylpyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 2-amino-6-cyclopropylpyrimidin-4(5H)-one

: 21573-09-1
4-chloro-6-cyclopropylpyrimidin-2-amine

Guidance literature:: With trichlorophosphate; for 4h; Heating;

Reference yield:

: 21573-08-0
2-amino-6-cyclopropylpyrimidin-4-ol

: 21573-09-1
4-chloro-6-cyclopropylpyrimidin-2-amine

Guidance literature:: With tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate; In acetonitrile; at 110 ℃; for 0.333333h;
DOI:10.1021/jm401727m

Reference yield:

: 32249-35-7
methyl 3-cyclopropyl-3-oxopropanoate

: 21573-09-1
4-chloro-6-cyclopropylpyrimidin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / methanol / 23 - 60 °C

2: tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 0.33 h / 110 °C

With potassium tert-butylate; tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate; In methanol; acetonitrile;
DOI:10.1021/jm401727m