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Technology Process of 1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride

1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride

Base Information
  • Chemical Name:1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride
  • CAS No.:130495-35-1
  • Molecular Formula:C22H26 N2 O3 . Cl H
  • Molecular Weight:402.9144
  • Hs Code.:2933290090
  • European Community (EC) Number:634-170-8
  • UNII:33BI32858P
  • DSSTox Substance ID:DTXSID70926763
  • Wikidata:Q27256259
  • ChEMBL ID:CHEMBL1256808
  • Mol file:130495-35-1.mol
1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride

Synonyms:1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole;SK and F 96365;SK and F-96365;SKF 96365;SKF-96365;SKF-96365 free base;SKF96365

Suppliers and Price of 1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • SKF 96365 hydrochloride
  • 10mg
  • $ 446.00
  • TRC
  • SKF-96365, Hydrochloride
  • 10mg
  • $ 180.00
  • Tocris
  • SKF-96365, Hydrochloride ≥99%(HPLC)
  • 50
  • $ 818.00
  • TCI Chemical
  • SKF-96365
  • 50MG
  • $ 538.00
  • TCI Chemical
  • SKF-96365
  • 10MG
  • $ 180.00
  • Sigma-Aldrich
  • SKF-96365 ≥98% (HPLC), solid
  • 5mg
  • $ 179.00
  • Sigma-Aldrich
  • SKF-96365, Hydrochloride Inhibits receptor-mediated Ca
  • 5mg-m
  • $ 158.00
  • Sigma-Aldrich
  • SKF-96365, Hydrochloride - CAS 130495-35-1 - Calbiochem Inhibits receptor-mediated Ca2+ entry in activated platelets, neutrophils, and endothelial cells at concentrations that do not affect internal Ca2+ release.
  • 5 mg
  • $ 146.15
  • DC Chemicals
  • SKF96365 >98%
  • 100 mg
  • $ 400.00
  • DC Chemicals
  • SKF96365 >98%
  • 250 mg
  • $ 800.00
Total 22 raw suppliers
Chemical Property of 1-(2-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole hydrochloride
Chemical Property:
  • Vapor Pressure:7.86E-12mmHg at 25°C 
  • Melting Point:119 °C 
  • Boiling Point:556°Cat760mmHg 
  • Flash Point:290.1°C 
  • PSA：45.51000 
  • Density:g/cm3 
  • LogP:5.09300 
  • Storage Temp.:Store at RT 
  • Solubility.:H2O: >20 mg/mL 
  • Water Solubility.:Soluble to 100mM in water 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:10
  • Exact Mass:402.1710204
  • Heavy Atom Count:28
  • Complexity:393
Purity/Quality:

99%, *data from raw suppliers

SKF 96365 hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): Xi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
  • Description SKF-96365 (130495-35-1) is an inhibitor of receptor-mediated calcium entry (RMCE) with IC50‘s of 8.5 μM for ADP stimulated platelets and 11.7 μM for thrombin stimulated platelets. Also inhibits Voltage-gated Ca2+ but not ATP-gated Ca2+ entry.1 It has also been shown to block transient receptor potential canonical type (TRPC) channels2, high-voltage-activated (HVA) L-type channels1, K channels3, sarcoplasmic reticulum Ca-ATPase4 and voltage-gated sodium channels5. SKF-96365 is a potent blocker of LVA T-type Ca channels, in particular Ca(V)3.1 (IC50 = 0.56 μM).6
  • Uses SKF 96365 Hydrochloride is a novel inhibitor of receptor-mediated calcium entry.
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