2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-

Base Information

Chemical Name:2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-
CAS No.:78819-23-5
Molecular Formula:C13H12O4
Molecular Weight:232.232
Hs Code.:
Nikkaji Number:J11.520G
Mol file:78819-23-5.mol

Synonyms:78819-23-5;2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-;Fadyenolide

Suppliers and Price of 2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-

Chemical Property:

Vapor Pressure:1.32E-07mmHg at 25°C
Boiling Point:430.3°Cat760mmHg
Flash Point:194.8°C
PSA：44.76000
Density:1.23g/cm³
LogP:2.08870
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:232.07355886
Heavy Atom Count:17
Complexity:362

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=O)OC1=C(C2=CC=CC=C2)OC
Isomeric SMILES:COC\1=CC(=O)O/C1=C(/C2=CC=CC=C2)\OC

Technology Process of 2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)-

There total 10 articles about 2(5H)-Furanone, 4-methoxy-5-(methoxyphenylmethylene)-, (5Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.7%

: 82204-21-5
methyl 5-(1-methoxybenzyl)tetronate

: 72031-58-4
(Z)-4-methoxy-5-benzylidenefuran-2(5H)-one

: 78819-23-5
5,6-Z-fadyenolide

: 78819-24-6
5,5-E-fadyenolide

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; for 10h; Yields of byproduct given; Heating;

Reference yield: 77.0%

: 82204-20-4
methyl 5-(1',1'-dimethoxybenzyl)tetronate

: 78819-23-5
5,6-Z-fadyenolide

Guidance literature:: With tert.-butyl lithium;
DOI:10.1016/S0040-4039(00)86829-X

Reference yield:

: 5873-86-9
methyl thiobenzoate

: C₅H₅O₃^(1-)*Na⁽¹⁺⁾

: 78819-23-5
5,6-Z-fadyenolide

: 78819-24-6
5,5-E-fadyenolide

Guidance literature:: C₅H₅O₃^(1-)*Na⁽¹⁺⁾; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

methyl thiobenzoate; With methyl iodide; In tetrahydrofuran; at -78 ℃; for 0.166667h; Inert atmosphere;

With sodium hexamethyldisilazane; In tetrahydrofuran; for 2h; Overall yield = 62percent; Overall yield = 144 mg; stereoselective reaction; Inert atmosphere; Reflux;
DOI:10.1021/acs.joc.0c02502