(1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride

Base Information

• Chemical Name: (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride
• CAS No.: 215871-44-6
• Molecular Formula: C₄H₈N₄*ClH
• Molecular Weight: 148.595
• European Community (EC) Number: 832-004-0
• Mol file: 215871-44-6.mol

Synonyms:(1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride;215871-44-6;MFCD23144165;(1-methyl-1,2,4-triazol-3-yl)methanamine;hydrochloride;(1-Methyl-1H-1,2,4-triazol-3-yl)methanamine HCl;1-(1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride;SCHEMBL6998701;PCAPKYZAZDKQNQ-UHFFFAOYSA-N;AKOS026742000;ES-2386;SB20505;DA-08182;SY151408;CS-0053658;EN300-124062;P18523;A905785;1-Methyl-1H-1,2,4-triazole-3-methanamine Hydrochloride;(1-methyl-1H-1,2,4-triazol-3-yl)methanaminehydrochloride;C-(1-methyl-1H-1,2,4-triazol-3-yl)methylamine hydrochloride;1-(1-METHYL-1,2,4-TRIAZOL-3-YL)METHANAMINE HYDROCHLORIDE

Chemical Property of (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride

Chemical Property:

• PSA: 56.73000
• LogP: 0.77610
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 148.0515740
• Heavy Atom Count: 9
• Complexity: 74.4

Purity/Quality:

97% ^*data from raw suppliers

(1-methyl-1H-1,2,4-triazol-3-yl)methanaminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C=NC(=N1)CN.Cl

Technology Process of (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride

There total 2 articles about (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-methyl-1,2,4-triazol-3-ylmethyl chloride (233278-54-1) → (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride (215871-44-6)

Guidance literature:

In ammonium hydroxide; ethanol;

Reference yield: 92.0%

(1-methyl-1H-[1,2,4]-triazol-3-yl)methanol (135242-93-2) → (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride (215871-44-6)

Guidance literature:

With ammonium hydroxide; thionyl chloride;

Reference yield:

6-Chloro-7-cyclobutyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazine (233278-53-0) + (1-methyl-1H-1,2,4-triazol-3-yl)methanamine hydrochloride (215871-44-6) → N-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N,N-dimethylamine (233278-52-9)

Guidance literature:

In triethylamine; N,N-dimethyl-formamide;

upstream raw materials:

1-methyl-1,2,4-triazol-3-ylmethyl chloride

(1-methyl-1H-[1,2,4]-triazol-3-yl)methanol

Downstream raw materials:

N-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N,N-dimethylamine