3-(3-Bromophenyl)-3-methyloxetane

Base Information

• Chemical Name: 3-(3-Bromophenyl)-3-methyloxetane
• CAS No.: 1123172-43-9
• Molecular Formula: C10H11BrO
• Molecular Weight: 227.101
• Hs Code.: 2932999099
• Mol file: 1123172-43-9.mol

Synonyms:3-(3-Bromophenyl)-3-methyloxetane

Chemical Property of 3-(3-Bromophenyl)-3-methyloxetane

Chemical Property:

• Boiling Point: 277.9±28.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.412±0.06 g/cm3(Predicted)
• LogP: 2.73700

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-(3-Bromophenyl)-3-methyloxetane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3-Bromophenyl)-3-methyloxetane

There total 1 articles about 3-(3-Bromophenyl)-3-methyloxetane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2-(3-bromophenyl)-2-methylpropane-1,3-diol (1123172-42-8) → 3-(3-bromophenyl)-3-methyloxetane (1123172-43-9)

Guidance literature:

With Ziram; triphenylphosphine; diethylazodicarboxylate; In toluene; at 20 ℃; for 18h;

Reference yield:

3-(3-bromophenyl)-3-methyloxetane (1123172-43-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-(3-methyloxetan-3-yl)benzaldehyde (1123172-40-6)

Guidance literature:

3-(3-bromophenyl)-3-methyloxetane; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; at 25 ℃; for 1h;

With water; ammonium chloride; In tetrahydrofuran;

upstream raw materials:

2-(3-bromophenyl)-2-methylpropane-1,3-diol

Downstream raw materials:

3-(3-methyloxetan-3-yl)benzaldehyde

Refernces

• 1、 -. "AMINOBENZYL-SUBSTITUTED CYCLIC SULFONES USEFUL AS BACE INHIBITORS". Page/Page column 20. . Retrieved 2009/04/24.