A1B1

Base Information

Chemical Name:A1B1
CAS No.:685534-25-2
Molecular Formula:C23H25ClFN3O2
Molecular Weight:429.922
Hs Code.:
Mol file:685534-25-2.mol

Synonyms:A1B1;ACETAMIDE, N-[5-CHLORO-2-[(1E)-3-[(2R)-4-[(4-FLUOROPHENYL)METHYL]-2-METHYL-1-PIPERAZINYL]-3-OXO-1-PROPENYL]PHENYL]-;N-(5-CHLORO-2-((E)-3-[(R)-4-(4-FLUORO-BENZYL)-2-METHYL-PIPERAZIN-1-YL]-3-OXO-PROPENYL)-PHENYL)-ACETAMIDE;Acetamide,N-[5-chloro-2-[(1E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-3-oxo-1-propen-1-yl]phenyl]-

Suppliers and Price of A1B1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
A1B1 95.00%
5MG
$ 502.44

Total 1 raw suppliers

Chemical Property of A1B1

Chemical Property:

PSA：52.65000
LogP:4.13240

Purity/Quality:

95% ^*data from raw suppliers

A1B1 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of A1B1

There total 2 articles about A1B1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 685534-24-1
(E)-3-(2-amino-4-chlorophenyl)-1-[(R)-4-(4-fluorobenzyl)-2-methylpiperazin-1-yl]-propenone

: 108-24-7
acetic anhydride

: 685534-25-2
N-(5-chloro-2-[(E)-3-[(R)-4-(4-fluorobenzyl)-2-methylpiperazin-1-yl]-3-oxopropenyl]phenyl)-acetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; for 8h; Heating / reflux;

Reference yield:

: 422270-29-9
(R)-1-(4-fluorobenzyl)-3-methylpiperazine

: (E)-3-(2-acetylamino-4-chloro-phenyl)-acrylic acid

: 685534-25-2
N-(5-chloro-2-[(E)-3-[(R)-4-(4-fluorobenzyl)-2-methylpiperazin-1-yl]-3-oxopropenyl]phenyl)-acetamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2005.08.057