1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine

Base Information

Chemical Name:1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine
CAS No.:127285-09-0
Molecular Formula:C14H22N2
Molecular Weight:218.342
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90466530
Mol file:127285-09-0.mol

Synonyms:127285-09-0;1-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]METHANAMINE;[1-(2-phenylethyl)piperidin-4-yl]methanamine;4-Piperidinemethanamine, 1-(2-phenylethyl)-;(1-Phenethylpiperidin-4-yl)methanamine;SCHEMBL3594852;DTXSID90466530;NPGJAUWAEIPXCP-UHFFFAOYSA-N;CFA28509;MFCD07365295;AKOS000210619;BS-35669;1-(2-phenylethyl)-4-piperidinemethylamine;1-(2- phenylethyl)-4-piperidinemethylamine;CS-0253528;FT-0761225;EN300-64643;1-[1-(2-Phenylethyl)-4-piperidinyl]methanamine;Z234897235;1-[1-(2-Phenylethyl)piperidin-4-yl]methanamine, AldrichCPR

Suppliers and Price of 1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[1-(2-Phenylethyl)piperidin-4-yl]methanamine
50mg
$ 45.00

Sigma-Aldrich
1-[1-(2-Phenylethyl)piperidin-4-yl]methanamine Aldrich
1g
$ 99.60

ChemBridge Corporation
1-[1-(2-phenylethyl)piperidin-4-yl]methanamine 95%
10 g
$ 179.20

American Custom Chemicals Corporation
[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]METHANAMINE 95.00%
1G
$ 765.23

AK Scientific
1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine
250mg
$ 139.00

Total 4 raw suppliers

Chemical Property of 1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:326.647°C at 760 mmHg
Flash Point:139.673°C
PSA：29.26000
Density:0.99g/cm³
LogP:2.53800
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:218.178298710
Heavy Atom Count:16
Complexity:179

Purity/Quality:

98%min ^*data from raw suppliers

1-[1-(2-Phenylethyl)piperidin-4-yl]methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CN)CCC2=CC=CC=C2

Technology Process of 1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine

There total 5 articles about 1-[1-(2-Phenylethyl)piperidin-4-YL]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: N-((1-phenethylpiperidin-4-yl)methyl)-1-phenylmethanimine

: 127285-09-0
1-[1-(2-phenylethyl)-4-piperidinyl]methanamine

Guidance literature:: With water; oxalic acid; In dichloromethane; for 3h; Reflux;
DOI:10.3390/ph13080161

Reference yield:

: 103-63-9
1-phenyl-2-bromoethane

: 71207-29-9
N-hexahydro-4-pyridinylmethyl-N-phenylmethylidenamine

: 127285-09-0
1-[1-(2-phenylethyl)-4-piperidinyl]methanamine

Guidance literature:: 1-phenyl-2-bromoethane; N-hexahydro-4-pyridinylmethyl-N-phenylmethylidenamine; With potassium carbonate; In ethanol; for 24h; Heating / reflux;

With hydrogenchloride; In water; at 20 ℃; for 2h;

With sodium hydroxide; In water; pH=~ 13;

Reference yield:

: 7144-05-0
4-Aminomethylpiperidine

: 127285-09-0
1-[1-(2-phenylethyl)-4-piperidinyl]methanamine

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 3 h / 25 °C

2: potassium carbonate / ethanol / 24 h / Reflux

3: water; hydrogenchloride / 2 h / 25 °C

With hydrogenchloride; water; potassium carbonate; In ethanol; toluene;
DOI:10.1002/cmdc.201800199