COMPLEMENT C2-DEPLETED SERUM, HUMAN

Base Information

• Chemical Name: COMPLEMENT C2-DEPLETED SERUM, HUMAN
• CAS No.: 80295-40-5
• Molecular Weight: 0

Synonyms:C2-DEPLETED SERUM, HUMAN;COMPLEMENT C2 DEFICIENT SERUM HUMAN;COMPLEMENT C2-DEPLETED SERUM, HUMAN;complement C2 deficient serum

Chemical Property of COMPLEMENT C2-DEPLETED SERUM, HUMAN

Chemical Property:

• Storage Temp.: −70°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Complement C2 deficient serum human for complement assays ^*data from reagent suppliers

Safty Information:

• Hazard Codes: B

MSDS Files:

Useful:

• Uses: C2 is a critical protease for compliment activation, which supports bacterial killing via phagocytes. C2 can be used in research to explore the mechanisms by which bacterial pathogens evade detection by the compliment system. One such mechanism by the bacteria Pseudomonas aeruginosa, uses the alkaline protease (AprA) to degrade and cleave C2 which ultimately interferes with the classical and lectin pathways. Research has shown that C2 deficiency results in an increased risk of infection by Streptococcus pyogenes through impaired phaogocytosis and neutrophil dependent killing.

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