1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid

Base Information

Chemical Name:1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid
CAS No.:915192-34-6
Molecular Formula:C12H14O4
Molecular Weight:222.241
Hs Code.:
Mol file:915192-34-6.mol

Synonyms:1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid;1-(2,6-dimethoxyphenyl)cyclopropane-1-carboxylicacid

Suppliers and Price of 1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid

Chemical Property:

PSA：55.76000
LogP:1.82000

Purity/Quality:: 99.0% MIN ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid

There total 4 articles about 1-(2,6-dimethoxyphenyl)Cyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1185886-64-9
methyl 1-(2-methoxy-6-methylphenyl)cyclopropanecarboxylate

: 915192-34-6
1-(2,6-dimethoxyphenyl)cyclopropane-1-carboxylic acid

Guidance literature:: With potassium trimethylsilonate; In tetrahydrofuran; at 65 ℃; for 3h; Inert atmosphere; Large scale reaction;
DOI:10.1021/jo901267x

Reference yield: 91.0%

: 915192-33-5
ethyl 1-(2,6-dimethoxyphenyl)cyclopropanecarboxylate

: 915192-34-6
1-(2,6-dimethoxyphenyl)cyclopropane-1-carboxylic acid

Guidance literature:: ethyl 1-(2,6-dimethoxyphenyl)cyclopropanecarboxylate; With methanol; sodium hydroxide; water; In tetrahydrofuran; for 96h;

With ammonium chloride; acetic acid; In tetrahydrofuran; water;

Reference yield:

: 915192-32-4
ethyl 2-(2,6-dimethoxyphenyl)acrylate

: 915192-34-6
1-(2,6-dimethoxyphenyl)cyclopropane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / dimethyl sulfoxide / 0.5 h / 20 °C

1.2: 3 h / 20 °C

2.1: methanol; sodium hydroxide; water / tetrahydrofuran / 96 h

With methanol; sodium hydroxide; potassium tert-butylate; water; In tetrahydrofuran; dimethyl sulfoxide;