2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid

Base Information

• Chemical Name: 2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid
• CAS No.: 86521-64-4
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257

Synonyms:2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid

Chemical Property of 2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid

Chemical Property:

Purity/Quality:

98%+ ^*data from raw suppliers

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Technology Process of 2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid

There total 2 articles about 2，2-dimethyl-p-ethoxy phenyl acetic acid 2，2-dimethyl-p-ethoxy phenyl acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(4-ethoxyphenyl)-2,2-dimethylethanol (83493-63-4) → 2-(4-ethoxyphenyl)-2-methylpropionic acid (86521-64-4)

Guidance literature:

With 1-hydroxycyclohexyl phenyl ketone; sodium hydroxide; In 1,2-dimethoxyethane; at 80 ℃; chemoselective reaction; Sealed tube;

DOI:10.1021/acs.orglett.1c02188

Reference yield: 90.0%

C17H25BrO3 → 2-(4-ethoxyphenyl)-2-methylpropionic acid (86521-64-4)

Guidance literature:

With water; sodium hydroxide; In toluene; at 70 - 80 ℃; Reflux;

Reference yield: 96.2%

2-(4-ethoxyphenyl)-2-methylpropionic acid (86521-64-4) → 2-(4-ethoxyphenyl)-2,2-dimethylethanol (83493-63-4)

Guidance literature:

With potassium borohydride; zinc(II) chloride; In ethanol; at 30 - 60 ℃; Temperature; Solvent; Reagent/catalyst;

upstream raw materials:

2-(4-ethoxyphenyl)-2,2-dimethylethanol

Downstream raw materials:

2-(4-ethoxyphenyl)-2,2-dimethylethanol

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