2,2-Difluoro-4-Methylenepentanedioic acid

Base Information

• Chemical Name: 2,2-Difluoro-4-Methylenepentanedioic acid
• CAS No.: 1307857-45-9
• Molecular Formula: C₆H₆F₂O₄
• Molecular Weight: 180.108
• Hs Code.: 2917190090
• Mol file: 1307857-45-9.mol

Synonyms:2,2-Difluoro-4-Methylenepentanedioic acid

Chemical Property of 2,2-Difluoro-4-Methylenepentanedioic acid

Chemical Property:

• PSA: 74.60000
• LogP: 0.73720

Purity/Quality:

96% ^*data from raw suppliers

2,2-Difluoro-4-methylenepentanedioic acid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-Difluoro-4-Methylenepentanedioic acid

There total 1 articles about 2,2-Difluoro-4-Methylenepentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,5-diethyl 2,2-difluoro-4-methylenepentanedioate (1307857-46-0) → 2,2-difluoro-4-methylenepentanedioic acid (1307857-45-9)

Guidance literature:

1,5-diethyl 2,2-difluoro-4-methylenepentanedioate; With lithium hydroxide; In tetrahydrofuran; at 0 ℃; for 3h;

pH=1; Acidic conditions;

DOI:10.1021/ol2009544

upstream raw materials:

1,5-diethyl 2,2-difluoro-4-methylenepentanedioate