(S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate

Base Information

Chemical Name:(S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate
CAS No.:915375-33-6
Molecular Formula:C₁₃H₁₈N₄O₂
Molecular Weight:262.312
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50475562
Wikidata:Q82306168
Mol file:915375-33-6.mol

Synonyms:915375-33-6;(S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate;tert-butyl N-[(1S)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl]carbamate;(S)-tert-butyl 1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethylcarbamate;DTXSID50475562;(S)-tert-Butyl(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate;AKOS016007786;AM20080549;FT-0771390;tert-butyl (S)-(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate;tert-Butyl [(1S)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl]carbamate;Carbamic acid, N-[(1S)-1-(1,2,4-triazolo[4,3-a]pyridin-3-yl)ethyl]-, 1,1-dimethylethyl ester

Suppliers and Price of (S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-tert-Butyl(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate 95+%
1g
$ 353.00

American Custom Chemicals Corporation
(S)-TERT-BUTYL (1-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)ETHYL)CARBAMATE 95.00%
1G
$ 780.15

American Custom Chemicals Corporation
(S)-TERT-BUTYL (1-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-3-YL)ETHYL)CARBAMATE 95.00%
5MG
$ 503.91

Alichem
(S)-tert-Butyl(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate
1g
$ 400.00

Total 5 raw suppliers

Chemical Property of (S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate

Chemical Property:

PSA：68.52000
LogP:2.70590
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:262.14297583
Heavy Atom Count:19
Complexity:329

Purity/Quality:

≥99% ^*data from raw suppliers

(S)-tert-Butyl(1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=NN=C2N1C=CC=C2)NC(=O)OC(C)(C)C
Isomeric SMILES:C[C@@H](C1=NN=C2N1C=CC=C2)NC(=O)OC(C)(C)C

Technology Process of (S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate

There total 3 articles about (S)-tert-Butyl (1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 915375-26-7
[1-(N'-pyridin-2-yl-hydrazinocarbonyl)-ethyl]-carbamic acid tert-butyl ester

: 915375-33-6
(1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: With Lawessons reagent; In 1,2-dimethoxyethane; at 80 ℃; for 2h;
DOI:10.1016/j.tetlet.2006.08.075

Reference yield:

: 4930-98-7
pyrid-2-ylhydrazine

: 915375-33-6
(1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / BOP; N-methylmorpholine / CH₂Cl₂ / 2 h

2: 70 percent / Lawesson's reagent / 1,2-dimethoxy-ethane / 2 h / 80 °C

With Lawessons reagent; 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/j.tetlet.2006.08.075

Reference yield:

: 15761-38-3
L-N-Boc-Ala

: 915375-33-6
(1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / BOP; N-methylmorpholine / CH₂Cl₂ / 2 h

2: 70 percent / Lawesson's reagent / 1,2-dimethoxy-ethane / 2 h / 80 °C

With Lawessons reagent; 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/j.tetlet.2006.08.075