3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-

Base Information

Chemical Name:3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-
CAS No.:1263285-61-5
Molecular Formula:C₆H₉NO₂
Molecular Weight:127.143
Hs Code.:
Mol file:1263285-61-5.mol

Synonyms:3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-;4-(HydroxyMethyl)-3-azabicyclo[3.1.0]hexan-2-one

Suppliers and Price of 3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(Hydroxymethyl)-3-azabicyclo[3.1.0]hexan-2-one 95+%
1g
$ 1786.00

Chemenu
4-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-2-one 95%
1g
$ 1683.00

Total 4 raw suppliers

Chemical Property of 3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-

Chemical Property:

Purity/Quality:

≥99% ^*data from raw suppliers

4-(Hydroxymethyl)-3-azabicyclo[3.1.0]hexan-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)-

There total 11 articles about 3-Azabicyclo[3.1.0]hexan-2-one, 4-(hydroxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: (3R,5aR,6aS,6bS)-3-(4-methoxyphenyl)tetrahydro-1H-cyclopropa[3,4]pyrrolo[1,2-c]oxazol-5(3H)-one

: 187742-07-0,1263285-61-5
(1R,4S,5S)-4-(hydroxymethyl)-3-azabicyclo<3.1.0>hexan-2-one

Guidance literature:: With acetic acid; In tetrahydrofuran; at 100 ℃; for 1h;
DOI:10.1248/cpb.45.36

Reference yield: 33.0%

: 117857-89-3
(5aS,6aR,6bS)-3,3-dimethyltetrahydro-1H-cyclopropa[3,4]pyrrolo[1,2-c]oxazol-5(3H)-one

: 1263285-61-5
(1S,4S,5R)-4-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-2-one

Guidance literature:: With toluene-4-sulfonic acid; In water; acetonitrile; at 90 ℃; for 1h; Inert atmosphere;

Reference yield:

: 117747-64-5
2-Amino-1-((S)-2,2-dimethyl-4-vinyl-oxazolidin-3-yl)-ethanone

: 187742-07-0,1263285-61-5
(1R,4S,5S)-4-(hydroxymethyl)-3-azabicyclo<3.1.0>hexan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaNO₂, citric acid / 0 °C / pH 3

2: Pd(OAc)2 / toluene / 2 h / 80 °C

3: acetic acid (60 percent) / 16 h / Ambient temperature

With palladium diacetate; acetic acid; citric acid; sodium nitrite; In toluene;
DOI:10.1016/S0040-4039(00)86682-4