PMCDG dipivoxil

Base Information

Chemical Name:PMCDG dipivoxil
CAS No.:441785-26-8
Deprecated CAS:872968-04-2
Molecular Formula:C22H34N5O7P
Molecular Weight:511.508421
Hs Code.:
UNII:S9I9P4J8IU
DSSTox Substance ID:DTXSID90196062
Nikkaji Number:J3.616.617G
Wikidata:Q27289084
Metabolomics Workbench ID:149375
ChEMBL ID:CHEMBL1652128

Synonyms:((1-((2-amino-9H-purin-9-yl)methyl)cyclopropyl)oxy)methylphosphonic acid di(pivaloyloxymethyl) ester;((1-((2-amino-9H-purin-9-yl)methyl)cyclopropyl)oxy)methylphosphonic acid dipivoxyl;besifovir;LB-80380;PMCDG dipivoxyl

Suppliers and Price of PMCDG dipivoxil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of PMCDG dipivoxil

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:15
Exact Mass:527.21450006
Heavy Atom Count:36
Complexity:805

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)OCOP(=O)(COC1(CC1)CN2C=NC3=CN=C(N=C32)N)OCOC(=O)C(C)(C)C
Recent ClinicalTrials:Pharmacokinetics of Besifovir in Adults With Normal and Impaired Renal Function

Technology Process of PMCDG dipivoxil

There total 17 articles about PMCDG dipivoxil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: chloropentyl pivalate

: 441785-25-7
Besifovir

: 441785-26-8
LB-80380

Guidance literature:: With triethylamine; at 70 ℃;

Reference yield: 38.5%

: 18997-19-8
Chloromethyl pivalate

: 441785-25-7
Besifovir

: 441785-26-8
LB-80380

Guidance literature:: Besifovir; With triethylamine; In 1-methyl-pyrrolidin-2-one; at 60 ℃; for 0.5h;

Chloromethyl pivalate; In 1-methyl-pyrrolidin-2-one; at 25 ℃; for 48h;
DOI:10.1021/jm0305265