Chemical Property of 5-(piperazin-1-yl)pyridin-2-aMine
Chemical Property:
- Boiling Point:401.7±40.0 °C(Predicted)
- PKA:8.67±0.10(Predicted)
- PSA:54.91000
- Density:1.163±0.06 g/cm3(Predicted)
- LogP:0.39730
- Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
- Purity/Quality:
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97% *data from raw suppliers
5-?(1-?Piperazinyl)?-?2-?pyridinamine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Uses
5-?(1-?Piperazinyl)?-?2-?pyridinamine is a reagent used in the synthesis of anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.